Literature DB >> 3837123

Venepuncture pain can be reduced.

L Kurien, H Kollberg, A Uppfeldt.   

Abstract

A lidocaine-prilocaine cream, 'eutectic mixture of local anaesthetics' (EMLA) and placebo were compared regarding their ability to diminish venepuncture pain in Oriental infants and young children. The investigation was double-blind and randomized. Twenty-eight children (median age 30 months) were treated with a placebo and 27 (median age 24 months) with EMLA. All pain reactions were observed by the same investigator and classified according to a three-grade scale: no pain, slight pain and severe pain. Treatment with EMLA resulted in significantly lower pain scores than treatment with the placebo (z = 2.67, P less than 0.01). No adverse reactions were observed.

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Year:  1985        PMID: 3837123

Source DB:  PubMed          Journal:  J Trop Med Hyg        ISSN: 0022-5304


  5 in total

Review 1.  Topical anaesthesia for needle-related pain in newborn infants.

Authors:  Jann P Foster; Christine Taylor; Kaye Spence
Journal:  Cochrane Database Syst Rev       Date:  2017-02-04

Review 2.  Eutectic lidocaine/prilocaine cream. A review of the topical anaesthetic/analgesic efficacy of a eutectic mixture of local anaesthetics (EMLA).

Authors:  M M Buckley; P Benfield
Journal:  Drugs       Date:  1993-07       Impact factor: 9.546

3.  Local anaesthetic cream for the alleviation of pain during venepuncture in Tanzanian schoolchildren.

Authors:  U Hellgren; C M Kihamia; Z Premji; K Danielson
Journal:  Br J Clin Pharmacol       Date:  1989-08       Impact factor: 4.335

4.  EMLA cream does not influence efficacy and pain reduction during pulsed-dye laser treatment of port-wine stain: a prospective side-by-side comparison.

Authors:  Wenxin Yu; Tianyou Wang; Jiafang Zhu; Yajing Qiu; Hui Chen; Yunbo Jin; Xi Yang; Xiaojie Hu; Lei Chang; Yijie Chen; Gang Ma; Xiaoxi Lin
Journal:  Lasers Med Sci       Date:  2017-12-15       Impact factor: 3.161

5.  Percutaneous dermal drug delivery for local pain control.

Authors:  Sujatha Tadicherla; Brian Berman
Journal:  Ther Clin Risk Manag       Date:  2006-03       Impact factor: 2.423

  5 in total

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