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Literature DB >> 3827312

Instant effect of induced abortion on serum ceruloplasmin activity, copper and zinc levels.

H Ozgüneş, M S Beksaç, S Duru, K Kayakirilmaz.

Abstract

Serum ceruloplasmin activity, serum copper and zinc levels were determined in 20 patients aged 19-43 with normal pregnancies of first trimester (5-9 weeks) admitted to hospital for legal abortion. Blood samples were taken from each patient 30 min before and 3 h after induced abortion. Significantly reduced ceruloplasmin activity (P less than 0.01) and serum copper level (P less than 0.05) were observed following induced abortion while zinc level didn't demonstrate any significant change (P greater than 0.05). A high degree of correlation was observed between the ceruloplasmin activity and the serum copper level (r = 0.87). Ceruloplasmin activity and serum copper values seem to be an index of feto-placental function in early pregnancy.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Copper
Ceruloplasmin
Zinc

Year: 1987 PMID： 3827312 DOI： 10.1007/bf02134060

Source DB: PubMed Journal: Arch Gynecol ISSN： 0170-9925

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References

15 in total

10. Studies on copper metabolism. XIV. Copper, ceruloplasmin and oxidase activity in sera of normal human subjects, pregnant women, and patients with infection, hepatolenticular degeneration and the nephrotic syndrome.

Authors: H MARKOWITZ; C J GUBLER; J P MAHONEY; G E CARTWRIGHT; M M WINTROBE
Journal: J Clin Invest Date: 1955-10 Impact factor: 14.808

Instant effect of induced abortion on serum ceruloplasmin activity, copper and zinc levels.

1. Serum copper determinations in normal pregnancy and abortion.

2. Influence of estrogens on total serum copper and caeruloplasmin.

3. Serum copper levels in normal and pathologic pregnancies.

4. Serum copper concentration significantly less in abnormal pregnancies.

5. Measurement of ceruloplasmin from its oxidase activity in serum by use of o-dianisidine dihydrochloride.

6. Raised serum copper and caeruloplasmin levels in subjects taking oral contraceptives.

7. Ceruloplasmin and 5-hydroxyindole metabolism in pregnancy.

8. Reduced serum zinc concentration during pregnancy.

9. First trimester serum zinc concentrations in human pregnancy.

10. Studies on copper metabolism. XIV. Copper, ceruloplasmin and oxidase activity in sera of normal human subjects, pregnant women, and patients with infection, hepatolenticular degeneration and the nephrotic syndrome.