Literature DB >> 3825499

Epilepsy in the elderly: prognosis.

K Lühdorf, L K Jensen, A M Plesner.   

Abstract

251 patients were admitted with seizures after the age of 60 years to the county hospital of Frederiksberg during the period 1979-1983, 163 had not received anti-epileptic treatment prior to admission, of these 151 had been admitted with their first seizure, 88 had established epilepsy at the time of admission. Of patients not previously treated and observed for at least 12 months, 62% remained seizure-free throughout the study, while 47% with established epilepsy were seizure-free. Of those not previously treated, 72% entered remission within the first year with a slight increase during the subsequent years. The first year was crucial in determining the long-term prognosis. Compared to previous studies on the prognosis of epilepsy it seems that prognosis in the elderly is as good or even better. Measurement of S-drug-levels at the time of seizure recurrence suggests that suboptimal treatment and poor compliance are important factors, thus indicating the need for regular control and monitoring of S-drug-levels. The presence of paroxysmal activity in the EEG was significantly correlated to seizure recurrence. Thirty-three patients entered nursing homes during the study period. Deterioration in residence status was correlated to degree of dementia and to the presence of focal neurological signs but not to age or to the severity of epilepsy.

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Year:  1986        PMID: 3825499     DOI: 10.1111/j.1600-0404.1986.tb03534.x

Source DB:  PubMed          Journal:  Acta Neurol Scand        ISSN: 0001-6314            Impact factor:   3.209


  6 in total

1.  Clinical-neurophysiological features of motor lesions in patients with post-stroke epilepsy.

Authors:  A B Gekht; G S Burd; M V Selikhova; V V Belyakov; A V Lebedeva
Journal:  Neurosci Behav Physiol       Date:  1999 Sep-Oct

Review 2.  Treating epilepsy in the elderly: safety considerations.

Authors:  S Arroyo; G Kramer
Journal:  Drug Saf       Date:  2001       Impact factor: 5.606

3.  Idiopathic first seizure in adult life: who should be treated?

Authors:  C A van Donselaar; A T Geerts; R J Schimsheimer
Journal:  BMJ       Date:  1991-03-16

4.  Risk of recurrence after first unprovoked tonic-clonic seizure in adults.

Authors:  I Bora; B Seçkin; M Zarifoglu; F Turan; S Sadikoglu; E Ogul
Journal:  J Neurol       Date:  1995-02       Impact factor: 4.849

Review 5.  Seizures in elderly patients with dementia: epidemiology and management.

Authors:  Mario Mendez; Gerald Lim
Journal:  Drugs Aging       Date:  2003       Impact factor: 3.923

6.  Management of seizures in the elderly: a survey of UK geriatricians.

Authors:  I H Stolarek; A F Brodie; M J Brodie
Journal:  J R Soc Med       Date:  1995-12       Impact factor: 18.000

  6 in total

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