| Literature DB >> 3825178 |
J E Bright, A C Woodman, T C Marrs, S G Wood.
Abstract
A methaemoglobin former, 4-aminopropiophenone (p-aminopropiophenone, PAPP), which is active only after metabolic activation in vivo, exhibits a sex difference in male Beagle dogs and bitches. Bitches produced more methaemoglobin for a given dose of PAPP than male dogs. The probable reason for this difference was a lower rate of N-hydroxylation in male dogs.Entities:
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Year: 1987 PMID： 3825178 DOI： 10.3109/00498258709047177
Source DB: PubMed Journal: Xenobiotica ISSN： 0049-8254 Impact factor: 1.908