Literature DB >> 3821779

Anaerobic metabolism of 2-amino-3-methyl-3H-imidazo[4,5-f]quinoline (IQ) by human fecal flora.

M Bashir, D G Kingston, R J Carman, R L van Tassell, T D Wilkins.   

Abstract

Incubation of the heterocyclic cooked food mutagen IQ with mixed human fecal microflora under anaerobic conditions yielded 2-amino-3,6-dihydro-3-methyl-7H-imidazo[4,5-f]quinoline-7-one (2) as the major detectable metabolite.

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Year:  1987        PMID： 3821779     DOI： 10.1016/0165-7992(87)90027-3

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  3 in total

1.  1H nuclear magnetic resonance spectroscopy-based studies of the metabolism of food-borne carcinogen 2-amino-3-methylimidazo[4,5-f]quinoline by human intestinal microbiota.

Authors:  Christèle Humblot; Bruno Combourieu; Marja-Liisa Väisänen; Jean-Pierre Furet; Anne-Marie Delort; Sylvie Rabot
Journal:  Appl Environ Microbiol       Date:  2005-09       Impact factor: 4.792

Review 2.  Gut microbiome interactions with drug metabolism, efficacy, and toxicity.

Authors:  Ian D Wilson; Jeremy K Nicholson
Journal:  Transl Res       Date:  2016-08-13       Impact factor: 7.012

3.  Transport and Biotransformation of Gliclazide and the Effect of Deoxycholic Acid in a Probiotic Bacteria Model.

Authors:  Maja Ðanić; Bojan Stanimirov; Nebojša Pavlović; Saša Vukmirović; Jelena Lazić; Hani Al-Salami; Momir Mikov
Journal:  Front Pharmacol       Date:  2019-09-24       Impact factor: 5.810
  3 in total

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