| Literature DB >> 3819756 |
K Reiners, R W Gilliatt, A E Harding, J H O'Neill.
Abstract
In order to test the regenerative capacity of atrophic axons, a constricting ligature was placed around the proximal tibial nerve of the rabbit, and the nerve crushed at the ankle one week later. Axonal atrophy with altered g ratios was subsequently confirmed in fibres distal to the site of ligature and proximal to the site of crush. In nerves with tight proximal ligatures the reinnervation of plantar muscles and the subsequent recovery of distal motor latency were delayed, indicating impaired regeneration. This result may be relevant to the "double-crush" theory of nerve damage.Entities:
Mesh：
Year: 1987 PMID： 3819756 PMCID： PMC1033243 DOI： 10.1136/jnnp.50.1.6
Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154