Literature DB >> 3818942

Antibody to sialosyllactosaminylparagloboside in a patient with IgM paraproteinemia and polyradiculoneuropathy.

N Miyatani, H Baba, S Sato, K Nakamura, T Yuasa, T Miyatake.   

Abstract

Serum from a patient with IgM paraproteinemia and polyradiculoneuropathy, diagnosed as malignant lymphoma, reacted specifically with a ganglioside, sialosyllactosaminylparagloboside (SLPG), in human peripheral nerve but not with myelin-associated glycoprotein (MAG). This finding demonstrates the existence of anti-SLPG antibody in the patient's serum, suggesting that this antibody may play a role in the pathogenesis of neuropathy.

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Year:  1987        PMID： 3818942     DOI： 10.1016/0165-5728(87)90053-1

Source DB:  PubMed          Journal:  J Neuroimmunol        ISSN： 0165-5728            Impact factor:   3.478


  3 in total

1.  Ataxic polyneuropathy and anti-Pr2 IgM kappa M proteinemia.

Authors:  M Arai; H Yoshino; Y Kusano; Y Yazaki; Y Ohnishi; T Miyatake
Journal:  J Neurol       Date:  1992-03       Impact factor: 4.849

2.  Human monoclonal IgM with autoantibody activity against two gangliosides (GM1 and GD1b) in a patient with motor neuron syndrome.

Authors:  M O Jauberteau; N Gualde; J L Preud'Homme; M Rigaud; R Gil; J M Vallat; N Baumann
Journal:  Clin Exp Immunol       Date:  1990-05       Impact factor: 4.330

3.  Glycosphingolipid antigens in cultured bovine brain microvascular endothelial cells: sulfoglucuronosyl paragloboside as a target of monoclonal IgM in demyelinative neuropathy [corrected].

Authors:  T Kanda; H Yoshino; T Ariga; M Yamawaki; R K Yu
Journal:  J Cell Biol       Date:  1994-07       Impact factor: 10.539
  3 in total

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