Literature DB >> 3818785

Twice weekly vindesine, a phase II study in lung cancer.

P E Postmus, N H Mulder, D L Schipper, E G de Vries.   

Abstract

Vindesine 1.75 mg/m2, twice weekly for 2 weeks followed by 2 weeks rest, was given to 26 lung cancer patients. In 6 patients a partial response was seen (23%). Neurotoxicity was present in 15 patients after 1 course; in 6 patients this was the reason for stopping therapy. This regimen has no advantage over weekly vindesine.

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Year:  1987        PMID: 3818785     DOI: 10.1007/bf00389975

Source DB:  PubMed          Journal:  J Cancer Res Clin Oncol        ISSN: 0171-5216            Impact factor:   4.553


  3 in total

1.  Phase one study of twice-weekly vindesine.

Authors:  N H Mulder; P E Postmus; D T Sleijfer; E G de Vries; P H Willemse
Journal:  Eur J Cancer Clin Oncol       Date:  1985-12

2.  Vindesine chemotherapy in lung cancer.

Authors:  R B Natale; R J Gralla; R E Wittes; R B Golbey; C W Young
Journal:  Cancer Treat Rev       Date:  1980-09       Impact factor: 12.111

3.  Vindesine in the treatment of small cell anaplastic bronchogenic carcinoma.

Authors:  K Osterlind; P Dombernowsky; P G Sørensen; H H Hansen
Journal:  Cancer Treat Rep       Date:  1981 Mar-Apr
  3 in total
  1 in total

1.  Reduction of the local toxicity of intraperitoneal chemotherapy; an experimental model.

Authors:  R G Molloy; B Crowley; K T Moran; M P Brady
Journal:  Ir J Med Sci       Date:  1990-06       Impact factor: 1.568

  1 in total

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