Literature DB >> 3818144

Acute effects of pirenzepin on bronchospasm.

K Sertl, S Meryn, W Graninger, A Laggner, W Schlick, H Rameis.   

Abstract

The response to pirenzepin, a new acetylcholine receptor blocking agent, was assessed and compared to placebo in patients with reversible bronchoconstriction. A single intravenous injection of 20 mg of pirenzepin induced a significant reduction of airway resistance compared to placebo (p less than 0.05). The anticholinergic substance pirenzepin appears to be useful in the treatment of bronchospasm.

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Year:  1986        PMID: 3818144

Source DB:  PubMed          Journal:  Int J Clin Pharmacol Ther Toxicol        ISSN: 0174-4879


  2 in total

Review 1.  Muscarinic receptor subtypes: implications for lung disease.

Authors:  P J Barnes
Journal:  Thorax       Date:  1989-03       Impact factor: 9.139

2.  Muscarinic blockade of methacholine induced airway and parenchymal lung responses in anaesthetised rats.

Authors:  M K Tulić; J L Wale; F Peták; P D Sly
Journal:  Thorax       Date:  1999-06       Impact factor: 9.139

  2 in total

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