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Literature DB >> 3817589

Penetration of albendazole sulphoxide into hydatid cysts.

D L Morris, J B Chinnery, G Georgiou, G Stamatakis, B Golematis.

Abstract

The penetration of albendazole sulphoxide, the principal metabolite of albendazole into hydatid cysts (E granulosus) was measured by means of in vitro animal and clinical studies. The drug freely diffuses across the parasitic membranes. Cyst/serum concentrations of 22% were achieved in patients, longer pre-operative therapy produced higher concentrations.

Entities: Chemical Species

Mesh：

Substances：

Year: 1987 PMID： 3817589 PMCID： PMC1432736 DOI： 10.1136/gut.28.1.75

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

14 in total

1. The permeability of the membranes of experimental secondary cysts of Echinococcus granulosus to [14C]mebendazole.

Authors: I L Reisin; C A Rabito; C A Rotunno; M Cereijido
Journal: Int J Parasitol Date: 1977-06 Impact factor: 3.981

2. Albendazole in hydatid disease.

Authors: D L Morris; P W Dykes; B Dickson; S E Marriner; J A Bogan; F G Burrows
Journal: Br Med J (Clin Res Ed) Date: 1983-01-08

3. Bioavailability and tolerability of mebendazole in patients with inoperable hydatid disease.

Authors: A D Bryceson; R Woestenborghs; M Michiels; H van den Bossche
Journal: Trans R Soc Trop Med Hyg Date: 1982 Impact factor: 2.184

4. Echinococcus granulosus: permeability of hydatid cysts to mebendazole in mice.

Authors: W S Kammerer; K L Miller
Journal: Int J Parasitol Date: 1981-06 Impact factor: 3.981

5. Chemotherapy of human hydatid disease with mebendazole. Follow-up of 16 cases.

Authors: A Bekhti; M Nizet; M Capron; J P Dessaint; F Santoro; A Capron
Journal: Acta Gastroenterol Belg Date: 1980 Jan-Feb Impact factor: 1.316

Review 6. Chemotherapy for larval echinococcosis in animals and humans: report of a workshop.

Authors: P M Schantz; H Van den Bossche; J Eckert
Journal: Z Parasitenkd Date: 1982

7. Analysis of benzimidazoles in body fluids by high-performance liquid chromatography.

Authors: J A Bogan; S Marriner
Journal: J Pharm Sci Date: 1980-04 Impact factor: 3.534

8. Clinical pharmacokinetics of high dose mebendazole in patients treated for cystic hydatid disease.

Authors: P A Braithwaite; M S Roberts; R J Allan; T R Watson
Journal: Eur J Clin Pharmacol Date: 1982 Impact factor: 2.953

9. Pharmacokinetics of albendazole in man.

Authors: S E Marriner; D L Morris; B Dickson; J A Bogan
Journal: Eur J Clin Pharmacol Date: 1986 Impact factor: 2.953

10. Long-term high-dose mebendazole for cystic hydatid disease of liver: failure in two cases.

Authors: P A Braithwaite
Journal: Aust N Z J Surg Date: 1981-02

16 in total

1. Efficacies of albendazole sulfoxide and albendazole sulfone against In vitro-cultivated Echinococcus multilocularis metacestodes.

Authors: K Ingold; P Bigler; W Thormann; T Cavaliero; B Gottstein; A Hemphill
Journal: Antimicrob Agents Chemother Date: 1999-05 Impact factor: 5.191

Review 2. Anthelminthic agents: some recent developments and their clinical application.

Authors: G C Cook
Journal: Postgrad Med J Date: 1991-01 Impact factor: 2.401

Review 3. Tropical medicine.

Authors: G C Cook
Journal: Postgrad Med J Date: 1991-09 Impact factor: 2.401

4. A long-surviving patient with recurrences of hepatic alveolar echinococcosis after traumatic intra-abdominal rupture.

Authors: N Sato; T Namieno; H Takahashi; K Yamashita; T Matsuhisa; S Aoki; J Uchino
Journal: J Gastroenterol Date: 1996-12 Impact factor: 7.527

5. Serology in patients treated with albendazole for hydatid disease.

Authors: M H Wilcox; D L Morris; J W Bailey
Journal: J R Soc Med Date: 1988-12 Impact factor: 5.344

6. Preoperative albendazole and scolices viability in patients with hepatic echinococcosis.

Authors: Carlos Manterola; Juan A Mansilla; Flery Fonseca
Journal: World J Surg Date: 2005-06 Impact factor: 3.352

7. A combined medical and surgical approach to hydatid disease: 12 years' experience at the Hospital for Tropical Diseases, London.

Authors: H M Ayles; E L Corbett; I Taylor; A G A Cowie; J Bligh; K Walmsley; A D M Bryceson
Journal: Ann R Coll Surg Engl Date: 2002-03 Impact factor: 1.891