| Literature DB >> 3814216 |
W Gau, J Kurz, U Petersen, H J Ploschke, C Wuensche.
Abstract
After oral administration of 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazine-1-ylquinoline++ +-3-carboxylic acid (ciprofloxacin, Bay o 9867; designated trademark: Ciprobay) four metabolites M1-M4 were isolated from human urine by Craig counter current distribution and semipreparative high-performance liquid chromatography. Their molecular structures were elucidated by nuclear magnetic resonance and mass spectrometry and confirmed by comparing their spectra with those of authentic synthetic reference compounds.Entities:
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Year: 1986 PMID： 3814216
Source DB: PubMed Journal: Arzneimittelforschung ISSN： 0004-4172