Literature DB >> 3814141

Immunochemical characterization of protein kinase C in rat liver nuclei and subnuclear fractions.

S Capitani, P R Girard, G J Mazzei, J F Kuo, R Berezney, F A Manzoli.   

Abstract

A doublet of immunoreactive bands has been identified in rat liver nuclei, nuclear matrix and lamina by means of a polyclonal antibody against protein kinase C. The two polypeptides show an apparent molecular weight of 77 and 74 kDa on SDS-polyacrylamide gels, and appear to be tightly bound nuclear components, resistant to detergent and high salt extraction. Given the complexity of the genes encoding for protein kinase C, these two forms of the enzyme might be translational products specifically located in the nucleus, involved in the transduction to the genomic apparatus of regulatory signals generated by growth factors and tumor promoters.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3814141     DOI： 10.1016/0006-291x(87)90283-x

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  11 in total

1.  Synthesis of polyphosphoinositides in nuclei of Friend cells. Evidence for polyphosphoinositide metabolism inside the nucleus which changes with cell differentiation.

Authors:  L Cocco; R S Gilmour; A Ognibene; A J Letcher; F A Manzoli; R F Irvine
Journal:  Biochem J       Date:  1987-12-15       Impact factor: 3.857

2.  Identification of intracellular receptor proteins for activated protein kinase C.

Authors:  D Mochly-Rosen; H Khaner; J Lopez
Journal:  Proc Natl Acad Sci U S A       Date:  1991-05-01       Impact factor: 11.205

3.  Phospholipase C digestion induces the removal of nuclear RNA: a cytochemical quantitative study.

Authors:  N Zini; N M Maraldi; A M Martelli; A Antonucci; P Santi; G Mazzotti; R Rizzoli; F A Manzoli
Journal:  Histochem J       Date:  1989-08

4.  Immunocytochemical evaluation of protein kinase C translocation to the inner nuclear matrix in 3T3 mouse fibroblasts after IGF-I treatment.

Authors:  N Zini; A M Martelli; L M Neri; A Bavelloni; P Sabatelli; S Santi; N M Maraldi
Journal:  Histochem Cell Biol       Date:  1995-06       Impact factor: 4.304

Review 5.  Protein kinase C in the immune system: from signalling to chromatin regulation.

Authors:  Pek Siew Lim; Christopher Ray Sutton; Sudha Rao
Journal:  Immunology       Date:  2015-10-06       Impact factor: 7.397

6.  Rapid activation of protein kinase C in isolated rat liver nuclei by prolactin, a known hepatic mitogen.

Authors:  A R Buckley; P D Crowe; D H Russell
Journal:  Proc Natl Acad Sci U S A       Date:  1988-11       Impact factor: 11.205

7.  Properties of protein kinase C associated with nuclear membranes.

Authors:  K Buchner; H Otto; R Hilbert; C Lindschau; H Haller; F Hucho
Journal:  Biochem J       Date:  1992-09-01       Impact factor: 3.857

8.  Prolactin-provoked alterations of cytosolic, membrane, and nuclear protein kinase C following partial hepatectomy.

Authors:  A R Buckley; P D Crowe; P A Bauman; L A Neumayer; H E Laird; D H Russell; C W Putnam
Journal:  Dig Dis Sci       Date:  1991-09       Impact factor: 3.199

9.  Protein kinase Czeta attenuates hypoxia-induced proliferation of fibroblasts by regulating MAP kinase phosphatase-1 expression.

Authors:  Megan D Short; Stephanie M Fox; Ching F Lam; Kurt R Stenmark; Mita Das
Journal:  Mol Biol Cell       Date:  2006-02-08       Impact factor: 4.138

10.  Type 3 protein kinase C localization to the nuclear envelope of phorbol ester-treated NIH 3T3 cells.

Authors:  K L Leach; E A Powers; V A Ruff; S Jaken; S Kaufmann
Journal:  J Cell Biol       Date:  1989-08       Impact factor: 10.539
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.