| Literature DB >> 3814114 |
K Sekiguchi, A M Klos, S Hirohashi, S Hakomori.
Abstract
The isotype of fibronectin present in human adult and fetal lung tissues was studied by limited proteolysis by cathepsin D followed by immunoblot analysis with domain-specific antibodies. The results indicate that the fibronectin in the adult lung tissue is predominantly the plasma-type whereas the fibronectin in the fetal lung tissue is more related to the cellular-type than to the plasma-type. Thus, it appears that the fibronectin isotype in tissue switches from the cellular-type to the plasma-type during ontogenesis.Entities:
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Year: 1986 PMID： 3814114 DOI： 10.1016/s0006-291x(86)80145-0
Source DB: PubMed Journal: Biochem Biophys Res Commun ISSN： 0006-291X Impact factor: 3.575