Literature DB >> 3813685

Common pancreaticobiliary channels and their relationship to gallstone size in gallstone pancreatitis.

B A Jones, B B Salsberg, M H Mehta, J M Bohnen.   

Abstract

Bile reflux into the pancreatic duct after impaction of a stone in a common pancreaticobiliary channel has been suggested to be the initiating factor in gallstone pancreatitis. Such reflux would require that the impacted stone be smaller than the length of the common channel. The incidence of common channels was studied and gallstone size was compared with common channel length in patients with gallstone pancreatitis and those with cholelithiasis or choledocholithiasis without pancreatitis. Sixty-seven per cent of patients with gallstone pancreatitis had a common channel present on intraoperative cholangiography versus 32% of patients with cholelithiasis or choledocholithiasis without pancreatitis (p less than 0.005). Common channel length was greater than the diameter of the smallest stone in nine of 27 patients with gallstone pancreatitis and in 13 of 109 patients with cholelithiasis or choledocholithiasis without pancreatitis (p less than 0.025). In conclusion, common channels are more frequent in patients with gallstone pancreatitis than in patients with other biliary tract disease. Furthermore, gallstone pancreatitis is associated with stones that are smaller than the common channel, which favors obstruction of both pancreatic and bile ducts while allowing reflux of contents between them.

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Year:  1987        PMID: 3813685      PMCID: PMC1492837          DOI: 10.1097/00000658-198702000-00003

Source DB:  PubMed          Journal:  Ann Surg        ISSN: 0003-4932            Impact factor:   12.969


  17 in total

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Journal:  Ann Surg       Date:  1964-10       Impact factor: 12.969

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Journal:  Acta Chir Scand       Date:  1958-03-08

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Journal:  Arch Surg       Date:  1976-10

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Journal:  Br J Surg       Date:  1979-06       Impact factor: 6.939

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Journal:  Ann Surg       Date:  1979-05       Impact factor: 12.969

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Journal:  Br J Surg       Date:  1975-06       Impact factor: 6.939

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Authors:  T R Kelly
Journal:  Surgery       Date:  1976-10       Impact factor: 3.982

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Authors:  T R Kelly; P E Swaney
Journal:  Surgery       Date:  1982-10       Impact factor: 3.982

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Authors:  D W ELLIOTT; R D WILLIAMS; R M ZOLLINGER
Journal:  Ann Surg       Date:  1957-10       Impact factor: 12.969

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  13 in total

Review 1.  Early endoscopic management of acute gallstone pancreatitis--an evidence-based review.

Authors:  A N Barkun
Journal:  J Gastrointest Surg       Date:  2001 May-Jun       Impact factor: 3.452

Review 2.  Biliary pancreatitis.

Authors:  George Sarosi; Robert V Rege
Journal:  J Gastrointest Surg       Date:  2006 Sep-Oct       Impact factor: 3.452

3.  A study on the human pancreaticobiliary duct system and ampulla region with their clinical considerations.

Authors:  Lokadolalu Chandracharya Prasanna; Antony Sylvan D'Souza; K V Rajagopal; Kumar M R Bhat
Journal:  Indian J Gastroenterol       Date:  2015-03-04

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Authors:  P D Hardt; L Bretz; A Krauss; H Schnell-Kretschmer; O Wusten; J Nalop; T Zekorn; H U Klör
Journal:  Dig Dis Sci       Date:  2001-03       Impact factor: 3.199

5.  Deoxycholic acid inhibited proliferation and induced apoptosis and necrosis by regulating the activity of transcription factors in rat pancreatic acinar cell line AR42J.

Authors:  Guixin Zhang; Jingwen Zhang; Dong Shang; Bing Qi; Hailong Chen
Journal:  In Vitro Cell Dev Biol Anim       Date:  2015-05-20       Impact factor: 2.416

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Authors:  C Schleicher; J C Baas; H Elser; N Senninger
Journal:  Ann Surg       Date:  2001-04       Impact factor: 12.969

7.  Bile acids induce pancreatic acinar cell injury and pancreatitis by activating calcineurin.

Authors:  Kamaldeen A Muili; Dong Wang; Abrahim I Orabi; Sheharyar Sarwar; Yuhuan Luo; Tanveer A Javed; John F Eisses; Syeda M Mahmood; Shunqian Jin; Vijay P Singh; Meena Ananthanaravanan; George Perides; John A Williams; Jeffery D Molkentin; Sohail Z Husain
Journal:  J Biol Chem       Date:  2012-11-12       Impact factor: 5.157

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Authors:  S P Misra; P Gulati; V Choudhary; B S Anand
Journal:  Gut       Date:  1990-09       Impact factor: 23.059

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Authors:  S P Misra; M Dwivedi
Journal:  Gut       Date:  1990-10       Impact factor: 23.059

Review 10.  Do gallstones cause chronic pancreatitis?

Authors:  S P Misra; M Dwivedi
Journal:  Int J Pancreatol       Date:  1991-09
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