Literature DB >> 3813518

Comparative efficacy of ketoconazole and mebendazole in experimental trichinosis.

J A Hess, P H Chandrasekar, M Mortiere, J A Molinari.   

Abstract

The therapeutic efficacy of ketoconazole and mebendazole was studied in ICR/CD-1 mice infected with Trichinella spiralis for 17 to 20 weeks. Efficacy of both drugs was over 70% when compared with results in control mice. This study indicates that both ketoconazole and mebendazole should be considered in the treatment of trichinosis in humans.

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Year:  1986        PMID： 3813518      PMCID： PMC180629          DOI： 10.1128/AAC.30.6.953

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  10 in total

1.  Treatment of trichinosis with mebendazole.

Authors:  M L Levin
Journal:  Am J Trop Med Hyg       Date:  1983-09       Impact factor: 2.345

2.  Imidazole and polyene activity against chloroquine-resistant Plasmodium falciparum.

Authors:  M A Pfaller; D J Krogstad
Journal:  J Infect Dis       Date:  1981-10       Impact factor: 5.226

3.  Activity of imidazoles against Leishmania tropica in human macrophage cultures.

Authors:  J D Berman
Journal:  Am J Trop Med Hyg       Date:  1981-05       Impact factor: 2.345

4.  Oral ketoconazole in the treatment of leishmaniasis.

Authors:  F G Urcuyo; N Zaias
Journal:  Int J Dermatol       Date:  1982-09       Impact factor: 2.736

5.  The treatment of trichinosis with mebendazole.

Authors:  J J Sonnet; D Thienpont
Journal:  Acta Clin Belg       Date:  1977       Impact factor: 1.264

6.  The effects of mebendazole and fenbendazole on Trichinella spiralis in mice.

Authors:  S S Fernando; D A Deham
Journal:  J Parasitol       Date:  1976-12       Impact factor: 1.276

7.  Ketoconazole in the treatment of paracoccidioidomycosis and histoplasmosis.

Authors:  R Negroni; A M Robles; A Arechavala; M A Tuculet; R Galimberti
Journal:  Rev Infect Dis       Date:  1980 Jul-Aug

8.  Mebendazole therapy of parenteral trichinellosis.

Authors:  R O McCracken; D D Taylor
Journal:  Science       Date:  1980-03-14       Impact factor: 47.728

9.  Interaction of anthelmintic benzimidazoles with Ascaris suum embryonic tubulin.

Authors:  P A Friedman; E G Platzer
Journal:  Biochim Biophys Acta       Date:  1980-06-19

10.  Ketoconazole protects against infection with Trypanosoma cruzi in a murine model.

Authors:  R E McCabe; F G Araujo; J S Remington
Journal:  Am J Trop Med Hyg       Date:  1983-09       Impact factor: 2.345
  10 in total
  1 in total

1.  Enhanced bioavailability and anthelmintic efficacy of mebendazole in redispersible microparticles with low-substituted hydroxypropylcellulose.

Authors:  Paloma Marina de la Torre-Iglesias; Juan José García-Rodriguez; Guillermo Torrado; Susana Torrado; Santiago Torrado-Santiago; Francisco Bolás-Fernández
Journal:  Drug Des Devel Ther       Date:  2014-09-18       Impact factor: 4.162
  1 in total

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