Literature DB >> 38133

Solubilization of unconjugated bilirubin by bile salts.

U Wosiewitz, S Schroebler.   

Abstract

Freshly precipitated unconjugated bilirubin (UCB) is solubilized rapidly and to a large extent by the sodium salts of di- and trihydroxy bile acids. The solubilization effect depending on bile salt concentration, pH and ionic strength is based on micellar mechanisms.

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Year:  1979        PMID： 38133     DOI： 10.1007/bf01968199

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  2 in total

1.  Solubility of bilirubin in aqueous solutions.

Authors:  R C BURNSTINE; R SCHMID
Journal:  Proc Soc Exp Biol Med       Date:  1962-02

2.  A fluorescent probe study of the solubilisation of cholesterol by bile salt-phospholipid micelles.

Authors:  R Paul; P Balaram
Journal:  Biochem Biophys Res Commun       Date:  1978-04-14       Impact factor: 3.575
  2 in total
  7 in total

1.  Solubilization of unconjugated bilirubin and its calcium salts by ionic, amphoteric, and nonionic detergents.

Authors:  U Wosiewitz; U Leuschner
Journal:  Naturwissenschaften       Date:  1990-05

2.  Gallstone formation and gallbladder bile composition after colectomy in dogs.

Authors:  H Noshiro; M Hotokezaka; H Higashijima; T Iwamoto; S Nakahara; R Mibu; R D Soloway; K Chijiiwa
Journal:  Dig Dis Sci       Date:  1996-12       Impact factor: 3.199

3.  Bile pigment pharmacokinetics and absorption in the rat: therapeutic potential for enteral administration.

Authors:  A C Bulmer; J S Coombes; J T Blanchfield; I Toth; R G Fassett; S M Taylor
Journal:  Br J Pharmacol       Date:  2011-12       Impact factor: 8.739

4.  Unconjugated bilirubin in hepatic bile with brown pigment gallstones and cholangitis.

Authors:  T Nakano; M Tabata; F Nakayma
Journal:  Dig Dis Sci       Date:  1988-09       Impact factor: 3.199

5.  Metastable and equilibrium phase diagrams of unconjugated bilirubin IXα as functions of pH in model bile systems: Implications for pigment gallstone formation.

Authors:  Marvin D Berman; Martin C Carey
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2014-10-30       Impact factor: 4.052

6.  Interactions of unconjugated bilirubin with vesicles, cyclodextrins and micelles: new modeling and the role of high pKa values.

Authors:  Pasupati Mukerjee; J Donald Ostrow
Journal:  BMC Biochem       Date:  2010-03-29       Impact factor: 4.059

7.  Isoextraction studies of partition of UCB between chloroform and aqueous solution.

Authors:  J S Hahm; K N Park
Journal:  Korean J Intern Med       Date:  1987-07       Impact factor: 2.884
  7 in total

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