Literature DB >> 3812094

Effects of kinins on the isolated perfused rat kidney and evidence for the presence of renal B1 receptors.

J A Guimarães, M A Vieira, E Eich, T Maack.   

Abstract

The kinins, particularly lysyl-bradykinin (LBK), have a bimodal effect on the vasculature of isolated rat kidney. The vasorelaxant but not the vasoconstrictor effect of LBK seems to be mediated by prostaglandins. The vasoconstrictor action of LBK can be blocked by (L-Leu)8-des-Arg9-BK indicating that the rat kidney vasculature has B1 kinin-receptor which mediates the effects of kinins and/or their C-terminal metabolites.

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Year:  1986        PMID: 3812094     DOI: 10.1007/978-1-4684-5143-6_74

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


  1 in total

1.  Evidence for BK1 bradykinin-receptor-mediated prostaglandin formation in osteoblasts and subsequent enhancement of bone resorption.

Authors:  O Ljunggren; U H Lerner
Journal:  Br J Pharmacol       Date:  1990-10       Impact factor: 8.739

  1 in total

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