Literature DB >> 3811963

Effects of manganese chloride on the rat developing nervous system.

K Kristensson, H Eriksson, B Lundh, L O Plantin, L Wachtmeister, M el Azazi, C Morath, E Heilbronn.   

Abstract

Sprague-Dawley rats were exposed to sublethal doses of manganese chloride during their postnatal development period up to 44 days of age. They showed transient clinical signs of disease and a decreased homovanillic acid (HVA) content in the striatum and hypothalamus between 15 and 22 days of age. The manganese content in the brain was increased 20-40 times during this period as determined with neutron activation analyses. In spite of this no structural damage or signs of maturation disturbances in the nervous system were found. Interruption of manganese exposure reversed the changes in HVA content.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 3811963     DOI： 10.1111/j.1600-0773.1986.tb00182.x

Source DB:  PubMed          Journal:  Acta Pharmacol Toxicol (Copenh)        ISSN： 0001-6683


  8 in total

1.  Trace element excess in PKU diets?

Authors:  E Sievers; H D Oldigs; K Dörner; J Schaub
Journal:  J Inherit Metab Dis       Date:  1990       Impact factor: 4.982

2.  Short-term oral administration of several manganese compounds in mice: physiological and behavioral alterations caused by different forms of manganese.

Authors:  J Komura; M Sakamoto
Journal:  Bull Environ Contam Toxicol       Date:  1991-06       Impact factor: 2.151

3.  Effects of manganese oxide on monkeys as revealed by a combined neurochemical, histological and neurophysiological evaluation.

Authors:  H Eriksson; K Mägiste; L O Plantin; F Fonnum; K G Hedström; E Theodorsson-Norheim; K Kristensson; E Stålberg; E Heilbronn
Journal:  Arch Toxicol       Date:  1987       Impact factor: 5.153

4.  Modulation of Mn2+ accumulation in cultured rat neuronal and astroglial cells.

Authors:  G Tholey; L Megias-Megias; F C Wedler; M Ledig
Journal:  Neurochem Res       Date:  1990-07       Impact factor: 3.996

Review 5.  Windows of sensitivity to toxic chemicals in the motor effects development.

Authors:  Susan Z Ingber; Hana R Pohl
Journal:  Regul Toxicol Pharmacol       Date:  2015-12-11       Impact factor: 3.271

6.  Effect of long-term administration of manganese on biogenic amine levels in discrete striatal regions of rat brain.

Authors:  H Eriksson; S Lenngren; E Heilbronn
Journal:  Arch Toxicol       Date:  1987-04       Impact factor: 5.153

7.  Manganese(II) dynamics and distribution in glial cells cultured from chick cerebral cortex.

Authors:  F C Wedler; B W Ley; A A Grippo
Journal:  Neurochem Res       Date:  1989-11       Impact factor: 3.996

8.  Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.

Authors:  Michael Aschner; Sandra Ceccatelli; Mardas Daneshian; Ellen Fritsche; Nina Hasiwa; Thomas Hartung; Helena T Hogberg; Marcel Leist; Abby Li; William R Mundi; Stephanie Padilla; Aldert H Piersma; Anna Bal-Price; Andrea Seiler; Remco H Westerink; Bastian Zimmer; Pamela J Lein
Journal:  ALTEX       Date:  2016-07-25       Impact factor: 6.043
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.