| Literature DB >> 3806584 |
L M Werbel, M Angelo, D W Fry, D F Worth.
Abstract
Installation of a basic side chain on the ring nitrogen of ellipticine did, as expected, improve the DNA binding properties of these molecules as measured by an ethidium displacement assay. In vivo antitumor activity was not, however, improved.Entities:
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Year: 1986 PMID: 3806584 DOI: 10.1021/jm00157a040
Source DB: PubMed Journal: J Med Chem ISSN: 0022-2623 Impact factor: 7.446