| Literature DB >> 3806289 |
E Nussbaum, J C Maggi, R Mathis, S P Galant.
Abstract
The association of lipid-laden alveolar macrophages (LLAM) and gastroesophageal reflux (GER) was investigated prospectively in 115 patients in two groups. Group 1 included 74 children with chronic respiratory tract disorders and documented GER by prolonged esophageal pH monitoring, barium esophagram, and esophagoscopy; group 2 included 41 children with chronic respiratory tract disorders without GER. LLAM were present in 63 (85%) and eight (19%) children from groups 1 and 2, respectively (P less than 0.0001). Thus a strong association between the presence of LLAM and GER in children with chronic respiratory tract disorders was established. We suggest that LLAM from bronchial lavage may be a useful marker for tracheal aspiration in children with GER in whom chronic lung disease may subsequently develop.Entities:
Mesh：
Year: 1987 PMID： 3806289 DOI： 10.1016/s0022-3476(87)80152-x
Source DB: PubMed Journal: J Pediatr ISSN： 0022-3476 Impact factor: 4.406