Literature DB >> 3803693

Cellular energy charge in the heart and liver of the rat. The effects of ethanol and acetaldehyde.

E Gillam, L C Ward.   

Abstract

The effects of ethanol and acetaldehyde upon adenine nucleotide concentrations in rat heart and liver were determined. Ethanol administered either acutely (8 g kg 0.73) or chronically (20% solution in drinking water for 21 d) significantly decreased ATP concentrations, adenylate energy charge (EC) and adenylate kinase mass action ratio (gamma AK) in liver but affected gamma AK only in heart. Acetaldehyde treatment elicited similar effects but of lesser magnitude.

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Year:  1986        PMID: 3803693     DOI: 10.1016/0020-711x(86)90249-1

Source DB:  PubMed          Journal:  Int J Biochem        ISSN: 0020-711X


  2 in total

1.  Effect of ethanol on adenosine triphosphate, cytosolic free calcium, and cell injury in rat hepatocytes. Time course and effect of nutritional status.

Authors:  A Gasbarrini; A B Borle; P Caraceni; A Colantoni; H Farghali; F Trevisani; M Bernardi; D H Van Thiel
Journal:  Dig Dis Sci       Date:  1996-11       Impact factor: 3.199

2.  Quantitative analysis of intermediary metabolism in rat hepatocytes incubated in the presence and absence of ethanol with a substrate mixture including ketoleucine.

Authors:  J M Baranyai; J J Blum
Journal:  Biochem J       Date:  1989-02-15       Impact factor: 3.857

  2 in total

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