Literature DB >> 3803611

Stoichiometry of sodium- and chloride-coupled glycine transport in synaptic plasma membrane vesicles derived from rat brain.

M C Aragón, C Giménez, F Mayor.   

Abstract

The stoichiometric properties of the glycine transporter were studied in synaptic plasma membrane vesicles from rat brain. The present results, together with previous data from our laboratory, allow us to suggest a stoichiometry of 2 Na+ and 1 Cl- per glycine zwitterion for the translocation cycle catalyzed by the glycine carrier. We propose a kinetic model with an ordered mechanism for the binding/debinding of solutes.

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Year:  1987        PMID： 3803611     DOI： 10.1016/0014-5793(87)81562-4

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  12 in total

1.  Characteristics and regulation of glycine transport in Bergmann glia.

Authors:  Edith López; Irene Lee-Rivera; Ana María López-Colomé
Journal:  Neurochem Res       Date:  2005-12       Impact factor: 3.996

2.  Transient currents in the glycine cotransporter GlyT1 reveal different steps in transport mechanism.

Authors:  Francesca Cherubino; Elena Bossi; Andreea Miszner; Chiara Ghezzi; Antonio Peres
Journal:  J Mol Neurosci       Date:  2009-08-27       Impact factor: 3.444

Review 3.  Molecular biology of glycinergic neurotransmission.

Authors:  F Zafra; C Aragón; C Giménez
Journal:  Mol Neurobiol       Date:  1997-06       Impact factor: 5.590

4.  PKCβ-dependent phosphorylation of the glycine transporter 1.

Authors:  Javier Vargas-Medrano; Vicente Castrejon-Tellez; Fernando Plenge; Ivan Ramirez; Manuel Miranda
Journal:  Neurochem Int       Date:  2011-08-12       Impact factor: 3.921

5.  N[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine (NFPS) is a selective persistent inhibitor of glycine transport.

Authors:  K R Aubrey; R J Vandenberg
Journal:  Br J Pharmacol       Date:  2001-12       Impact factor: 8.739

Review 6.  Sodium ion-dependent transporters for neurotransmitters: a review of recent developments.

Authors:  D M Worrall; D C Williams
Journal:  Biochem J       Date:  1994-02-01       Impact factor: 3.857

7.  Active transport of gamma-aminobutyric acid and glycine into synaptic vesicles.

Authors:  P E Kish; C Fischer-Bovenkerk; T Ueda
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

8.  Bergmann glial GlyT1 mediates glycine uptake and release in mouse cerebellar slices.

Authors:  Hao Huang; Latifa Barakat; Doris Wang; Angélique Bordey
Journal:  J Physiol       Date:  2004-08-26       Impact factor: 5.182

9.  Pharmacological properties of glycine transport in the frog retina.

Authors:  Jorge A Pérez-León; Estuardo López-Vera; Rocío Salceda
Journal:  Neurochem Res       Date:  2004-01       Impact factor: 3.996

10.  Kinetic Models of Secondary Active Transporters.

Authors:  Verena Burtscher; Klaus Schicker; Michael Freissmuth; Walter Sandtner
Journal:  Int J Mol Sci       Date:  2019-10-28       Impact factor: 5.923
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