Literature DB >> 3801895

Olfactory bulbectomy protects against pilocarpine-induced motor limbic seizures in rats.

M H Millan, S Patel, B S Meldrum.   

Abstract

Systemic injection of pilocarpine (380 mg/kg) results in the development of motor limbic seizures in rats. Olfactory bulbectomy performed 7 days prior to pilocarpine administration has a strong protective effect against the seizures. Neuropathological changes which normally occur in this seizure model do not develop in the brains of bulbectomized animals.

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Year:  1986        PMID： 3801895     DOI： 10.1016/0006-8993(86)91271-0

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  4 in total

1.  Rapid alterations in diffusion-weighted images with anatomic correlates in a rodent model of status epilepticus.

Authors:  C J Wall; E J Kendall; A Obenaus
Journal:  AJNR Am J Neuroradiol       Date:  2000 Nov-Dec       Impact factor: 3.825

2.  Neuronal and glial cell populations in the piriform cortex distinguished by using an approximation of q-space imaging after status epilepticus.

Authors:  Shawnee Eidt; Edward J Kendall; André Obenaus
Journal:  AJNR Am J Neuroradiol       Date:  2004-08       Impact factor: 3.825

3.  The involvement of excitatory amino acid receptors within the prepiriform cortex in pilocarpine-induced limbic seizures in rats.

Authors:  M H Millan; S Patel; B S Meldrum
Journal:  Exp Brain Res       Date:  1988       Impact factor: 1.972

4.  Olfactory Bulbectomy Leads to the Development of Epilepsy in Mice.

Authors:  Yifei Jiang; Raymund Y K Pun; Katrina Peariso; Katherine D Holland; Qingquan Lian; Steve C Danzer
Journal:  PLoS One       Date:  2015-09-14       Impact factor: 3.240
  4 in total

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