| Literature DB >> 3799970 |
Abstract
At concentrations greater than approximately 0.5 microM, dethiobiotin can cause the bioassay for biotin, which employs Lactobacillus plantarum, to over value the actual biotin level. This can be as much as 30-fold at 10 microM DL-dethiobiotin and 5 pM biotin. Dethiobiotin does this by exerting a sparing effect on the biotin response by the assay organism. We demonstrate one way to determine the actual biotin concentration in the presence of interfering levels of dethiobiotin.Entities:
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Year: 1986 PMID： 3799970 DOI： 10.1016/0003-2697(86)90587-7
Source DB: PubMed Journal: Anal Biochem ISSN： 0003-2697 Impact factor: 3.365