Literature DB >> 3798869

A new platelet antigen system, Yuka/Yukb.

Y Shibata, T Miyaji, Y Ichikawa, I Matsuda.   

Abstract

We report a new platelet antigen (Yukb) involved in a case of neonatal alloimmune thrombocytopenia (NAITP). This antigen is considered to be a product of an allele of the Yuk gene, another allele of which codes for Yuka which was involved in 2 cases of NAITP. The Yuka and Yukb antigens are not expressed on thrombasthenic platelets which suggests that these antigens are present on platelet glycoprotein IIb and/or IIIa. The gene frequencies for Yuka and Yukb in the Japanese population were estimated to be 0.0083 and 0.9917, respectively.

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Year:  1986        PMID: 3798869     DOI: 10.1111/j.1423-0410.1986.tb01980.x

Source DB:  PubMed          Journal:  Vox Sang        ISSN: 0042-9007            Impact factor:   2.144


  4 in total

1.  On the association of the platelet-specific alloantigen, Pena, with glycoprotein IIIa. Evidence for heterogeneity of glycoprotein IIIa.

Authors:  K Furihata; D J Nugent; A Bissonette; R H Aster; T J Kunicki
Journal:  J Clin Invest       Date:  1987-12       Impact factor: 14.808

2.  Localization of human platelet autoantigens to the cysteine-rich region of glycoprotein IIIa.

Authors:  R Kekomaki; B Dawson; J McFarland; T J Kunicki
Journal:  J Clin Invest       Date:  1991-09       Impact factor: 14.808

3.  An amino acid polymorphism within the RGD binding domain of platelet membrane glycoprotein IIIa is responsible for the formation of the Pena/Penb alloantigen system.

Authors:  R Wang; K Furihata; J G McFarland; K Friedman; R H Aster; P J Newman
Journal:  J Clin Invest       Date:  1992-11       Impact factor: 14.808

4.  A case of neonatal alloimmune thrombocytopenia in the presence of both anti-HPA-4b and anti-HPA-5b antibody: clinical and serological analysis of the subsequent pregnancy.

Authors:  Tomoko Kiyokawa; Yangsook Koh; Kazuya Mimura; Kotarosumitomo Nakayama; Mika Hosokawa; Mikiko Sakuragi; Tamayo Morikawa; Mayumi Nakao; Hiroshi Aochi; Yasuo Fukumori; Takeshi Kanagawa; Keisuke Nagamine; Tadashi Kimura; Yoshiaki Tomiyama
Journal:  Int J Hematol       Date:  2014-06-28       Impact factor: 2.490

  4 in total

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