Literature DB >> 3796837

Parkinson's disease and dementia: norepinephrine and dopamine in locus ceruleus.

R Cash, T Dennis, R L'Heureux, R Raisman, F Javoy-Agid, B Scatton.   

Abstract

Norepinephrine, 3-methoxy 4-hydroxyphenylethyleneglycol and homovanillic acid levels were similar in the locus ceruleus of 13 controls and 8 parkinsonian patients with no intellectual deterioration, but were decreased in 7 demented patients. The concentration of dopamine was similarly diminished in non-demented and demented parkinsonians, and binding of 3H-desmethylimipramine and 3H-rauwolscine was not abnormal in parkinsonians. These data indicate that norepinephrine metabolism in the locus ceruleus is subnormal only in demented parkinsonians.

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Year:  1987        PMID： 3796837     DOI： 10.1212/wnl.37.1.42

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  41 in total

1.  Reduced noradrenergic innervation of ventral midbrain dopaminergic cell groups and the subthalamic nucleus in MPTP-treated parkinsonian monkeys.

Authors:  Gunasingh Jeyaraj Masilamoni; Olivia Groover; Yoland Smith
Journal:  Neurobiol Dis       Date:  2016-12-30       Impact factor: 5.996

2.  Cognitive improvement during Tolcapone treatment in Parkinson's disease.

Authors:  M Gasparini; E Fabrizio; V Bonifati; G Meco
Journal:  J Neural Transm (Vienna)       Date:  1997       Impact factor: 3.575

Review 3.  Monoamine reuptake inhibitors in Parkinson's disease.

Authors:  Philippe Huot; Susan H Fox; Jonathan M Brotchie
Journal:  Parkinsons Dis       Date:  2015-02-25

Review 4.  Neuropsychiatric aspects of Parkinson's disease: recent advances.

Authors:  Laura Marsh; Ariel Berk
Journal:  Curr Psychiatry Rep       Date:  2003-05       Impact factor: 5.285

Review 5.  Management of Parkinson's disease dementia : practical considerations.

Authors:  Arvid Rongve; Dag Aarsland
Journal:  Drugs Aging       Date:  2006       Impact factor: 3.923

6.  Does cognitive impairment in Parkinson's disease result from non-dopaminergic lesions?

Authors:  B Pillon; B Dubois; G Cusimano; A M Bonnet; F Lhermitte; Y Agid
Journal:  J Neurol Neurosurg Psychiatry       Date:  1989-02       Impact factor: 10.154

Review 7.  Human genetics of plasma dopamine beta-hydroxylase activity: applications to research in psychiatry and neurology.

Authors:  J F Cubells; C P Zabetian
Journal:  Psychopharmacology (Berl)       Date:  2004-04-16       Impact factor: 4.530

8.  6-Hydroxydopamine induced impairment of Pavlovian conditioning in the rabbit.

Authors:  L Winsky; J A Harvey
Journal:  Neurochem Res       Date:  1992-05       Impact factor: 3.996

9.  Histochemistry of MAO-A and MAO-B in the locus coeruleus of the Mongolian gerbil.

Authors:  C Konradi; K Jellinger; P Riederer; T Nagatsu
Journal:  J Neural Transm       Date:  1987       Impact factor: 3.575

10.  Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part II: physiological and pharmacological manipulations and pathological alterations of locus coeruleus activity in humans.

Authors:  E R Samuels; E Szabadi
Journal:  Curr Neuropharmacol       Date:  2008-09       Impact factor: 7.363
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