| Literature DB >> 3795879 |
A R Koslow, R R Stromberg, L I Friedman, R J Lutz, S L Hilbert, P Schuster.
Abstract
A parallel plate chamber in a flow system has been designed to study the effects of fluid shear stresses on cells. The system was applied to the study of cultured endothelial cells grown on cover slips which were accommodated in recessed wells in the base plate. Dye injection studies in the chamber indicated laminar flow over the cells. Shear rates measured over the cover slips by an electrochemical technique were found to be linear with flow rate. Laser doppler anemometry showed parabolic profiles between the plates. Endothelial cells subjected to flow showed a correlation between the time required for orientation and the magnitude of the shear stress.Mesh：
Year: 1986 PMID： 3795879 DOI： 10.1115/1.3138625
Source DB: PubMed Journal: J Biomech Eng ISSN： 0148-0731 Impact factor: 2.097