Literature DB >> 3794749

Neuropathology of acquired immunodeficiency syndrome (AIDS). Analysis of 22 Brazilian cases.

S Rosemberg, M B Lopes, A M Tsanaclis.   

Abstract

The neuropathologic study of 22 Brazilian cases of acquired immuno-deficiency syndrome (AIDS) was performed. Thirteen cases (59%) showed neuropathologic lesions. These included infection by Toxoplasma (n = 4), Cryptococcus neoformans (n = 3), viral encephalitis (n = 4), primary lymphomas (n = 2), isolated cerebral infarct (n = 1), and reactive gliosis (n = 1). In 2 cases, primary lymphoma and viral encephalitis were associated. Axonal spheroids in the gracilis and cuneatus nuclei were present in a case of toxoplasmosis. Mammillary bodies lesions consistent with Wernicke's encephalopathy were found in a case of viral encephalitis. In addition, circulatory changes (focal cortical infarcts) were associated lesions in 3 cases. These findings were compared with the main series reported in American and European literature.

Entities:  

Keywords:  Acquired Immunodeficiency Syndrome; Americas; Biology; Brazil; Developing Countries; Diseases; Examinations And Diagnoses; Hiv Infections; Laboratory Examinations And Diagnoses; Laboratory Procedures; Latin America; Measurement; Neurologic Effects; Physical Examinations And Diagnoses; Physiology; Prevalence; Research Methodology; Signs And Symptoms; South America; Viral Diseases

Mesh:

Year:  1986        PMID: 3794749     DOI: 10.1016/0022-510x(86)90168-1

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN: 0022-510X            Impact factor:   3.181


  10 in total

Review 1.  HTLV-1 and HIV infections of the central nervous system in tropical areas.

Authors:  P Cabre; D Smadja; A Cabié; C R Newton
Journal:  J Neurol Neurosurg Psychiatry       Date:  2000-05       Impact factor: 10.154

2.  The changing pattern of human immunodeficiency virus-associated cerebral toxoplasmosis: a study of 46 postmortem cases.

Authors:  C Strittmatter; W Lang; O D Wiestler; P Kleihues
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

3.  Wernicke's encephalopathy in two patients with acquired immunodeficiency syndrome.

Authors:  J Schwenk; G Gosztonyi; P Thierauf; J Iglesias; E Langer
Journal:  J Neurol       Date:  1990-11       Impact factor: 4.849

4.  Neuropathology of the acquired immune deficiency syndrome (AIDS): a report of 135 consecutive autopsy cases from Switzerland.

Authors:  W Lang; J Miklossy; J P Deruaz; G P Pizzolato; A Probst; T Schaffner; E Gessaga; P Kleihues
Journal:  Acta Neuropathol       Date:  1989       Impact factor: 17.088

5.  Cytomegalovirus (CMV) disease of the brain in AIDS and connatal infection: a comparative study by histology, immunocytochemistry and in situ DNA hybridization.

Authors:  M Schmidbauer; H Budka; W Ulrich; P Ambros
Journal:  Acta Neuropathol       Date:  1989       Impact factor: 17.088

6.  Neuropathology of HIV infection in haemophiliacs: comparative necropsy study.

Authors:  M M Esiri; F Scaravilli; P R Millard; J N Harcourt-Webster
Journal:  BMJ       Date:  1989-11-25

7.  Brain pathology induced by infection with the human immunodeficiency virus (HIV). A histological, immunocytochemical, and electron microscopical study of 100 autopsy cases.

Authors:  H Budka; G Costanzi; S Cristina; A Lechi; C Parravicini; R Trabattoni; L Vago
Journal:  Acta Neuropathol       Date:  1987       Impact factor: 17.088

8.  Nature, incidence and prognosis of neurological involvement in the acquired immunodeficiency syndrome in central London.

Authors:  R J Guiloff; G N Fuller; A Roberts; M Hargreaves; B Gazzard; F Scaravilli; J N Harcourt-Webster
Journal:  Postgrad Med J       Date:  1988-12       Impact factor: 2.401

9.  Thiamine deficiency and Wernicke's encephalopathy in AIDS.

Authors:  R F Butterworth; C Gaudreau; J Vincelette; A M Bourgault; F Lamothe; A M Nutini
Journal:  Metab Brain Dis       Date:  1991-12       Impact factor: 3.584

Review 10.  Susceptibility of the cerebellum to thiamine deficiency.

Authors:  Patrick J Mulholland
Journal:  Cerebellum       Date:  2006       Impact factor: 3.648

  10 in total

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