Literature DB >> 3793626

Microbial conversion of compactin (ML-236B) to ML-236A.

D Komagata, H Yamashita, A Endo.   

Abstract

Approximately 1,600 fungal strains were tested for ability to convert compactin (ML-236B) to ML-236A and Emericella unguis IFO 8087 was found to be the most active. E. unguis converted ML-236B to ML-236A with a yield of over 90%.

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Year:  1986        PMID: 3793626     DOI: 10.7164/antibiotics.39.1574

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  3 in total

1.  Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum.

Authors:  Kirsty J McLean; Marcus Hans; Ben Meijrink; Wibo B van Scheppingen; Aad Vollebregt; Kang Lan Tee; Jan-Metske van der Laan; David Leys; Andrew W Munro; Marco A van den Berg
Journal:  Proc Natl Acad Sci U S A       Date:  2015-02-17       Impact factor: 11.205

2.  Purification and Characterization of a Lovastatin Esterase from Clonostachys compactiuscula.

Authors:  T G Schimmel; W S Borneman; M J Conder
Journal:  Appl Environ Microbiol       Date:  1997-04       Impact factor: 4.792

Review 3.  Chemistry, biochemistry, and pharmacology of HMG-CoA reductase inhibitors.

Authors:  A Endo
Journal:  Klin Wochenschr       Date:  1988-05-16
  3 in total

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