Literature DB >> 3793505

153Sm radiotherapeutic bone agents.

W F Goeckeler, D E Troutner, W A Volkert, B Edwards, J Simon, D Wilson.   

Abstract

Samarium-153 is a radionuclide which can be produced in high yield by neutron irradiation and which has nuclear properties that make it attractive for use as a radiotherapeutic agent. Several phosphonate complexes of 153Sm were synthesized and characterized by electrophoresis and HPLC. A procedure based on cation exchange chromatography was developed for measuring complex yields. The complexes could be produced in yields greater than 99%, were anionic, and most exhibited a single HPLC peak.

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Year:  1986        PMID： 3793505     DOI： 10.1016/0883-2897(86)90028-0

Source DB:  PubMed          Journal:  Int J Rad Appl Instrum B        ISSN： 0883-2897


  7 in total

Review 1.  Bifunctional coupling agents for radiolabeling of biomolecules and target-specific delivery of metallic radionuclides.

Authors:  Shuang Liu
Journal:  Adv Drug Deliv Rev       Date:  2008-04-23       Impact factor: 15.470

2.  Synergistic activity of the proteasome inhibitor PS-341 with non-myeloablative 153-Sm-EDTMP skeletally targeted radiotherapy in an orthotopic model of multiple myeloma.

Authors:  Apollina Goel; Angela Dispenzieri; Susan M Geyer; Suzanne Greiner; Kah-Whye Peng; Stephen J Russell
Journal:  Blood       Date:  2006-01-19       Impact factor: 22.113

3.  A Phase II study of (153)Sm-EDTMP and high-dose melphalan as a peripheral blood stem cell conditioning regimen in patients with multiple myeloma.

Authors:  Angela Dispenzieri; Gregory A Wiseman; Martha Q Lacy; Suzanne R Hayman; Shaji K Kumar; Francis Buadi; David Dingli; Krista M Laumann; Jake Allred; Susan M Geyer; Mark R Litzow; Dennis A Gastineau; David J Inwards; Ivana N Micallef; Stephen M Ansell; Luis Porrata; Michelle A Elliott; Patrick B Johnston; William J Hogan; Morie A Gertz
Journal:  Am J Hematol       Date:  2010-06       Impact factor: 10.047

4.  Controlled size and morphology of EDTMP-doped hydroxyapatite nanoparticles as model for 153Samarium-EDTMP doping.

Authors:  Yuling Jamie Han; Say Chye Joachim Loo; Ngoc Thao Phung; Hooi Tin Ong; Stephen J Russell; Kah-Whye Peng; Freddy Boey; Jan Ma
Journal:  J Mater Sci Mater Med       Date:  2008-03-25       Impact factor: 3.896

Review 5.  Radiopharmaceuticals for Treatment of Osteosarcoma.

Authors:  Peter M Anderson
Journal:  Adv Exp Med Biol       Date:  2020       Impact factor: 2.622

6.  Beyond Palliation: Therapeutic Applications of 153Samarium-EDTMP.

Authors:  Breelyn A Wilky; David M Loeb
Journal:  Clin Exp Pharmacol       Date:  2013-06

7.  Production, quality control, and bio-distribution studies of (159)Gd-EDTMP as a palliative agent for bone pain.

Authors:  Simindokht Shirvani Arani; Somaye Ghasemi; Ali Bahrami Samani; Mojtaba Shamsaei Zafarghandi
Journal:  Electron Physician       Date:  2015-03-01
  7 in total

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