| Literature DB >> 379332 |
D L Garmaise, D T Chu, E Bernstein, M Inaba, J M Stamm.
Abstract
Chelocardin (1) was condensed with numerous hydrazines, hydrazides, and anilines, yielding 2'-substituted derivatives with antibacterial spectra similar to the parent antibiotic. The hydrazone derivatives 9 and 10 and the two anilino derivatives 42 and 44 had more in vivo antibacterial activity than chelocardin.Entities:
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Year: 1979 PMID： 379332 DOI： 10.1021/jm00191a018
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446