Surrogate modeling of the effect of object motion on image degradation in radioscintigraphy.

Image degradation has been modeled for uniform, harmonic, parabolic and random motion using analytical functions. Parameters investigated include the modulation transfer function (MTF), the information transfer function (the square of the MTF), the optimum frequency response (peak of the MTF x k versus k curve) and the modulation index (the MTF at the optimum frequency response). The results of this modeling demonstrate that motion causes not only a major degradation in the resolution matrices investigated but also that some simulated motions cause phase shifts, a previously underappreciated phenomenon.