| Literature DB >> 3792141 |
M S Mooseker, T R Coleman, K A Conzelman.
Abstract
Calcium plays a central role in the regulation of cytoskeletal assembly, structure and contractility. In the case of actin there are a number of functional classes of actin-binding proteins which confer on a given actin filament its specific function in the cell. Among these various classes of actin-binding proteins are a subset of proteins whose activity is either regulated directly or indirectly (for example, through calmodulin) by Ca2+. This includes the regulation of actin-myosin interaction, actin assembly, actin filament interaction and the formation of supramolecular cytoskeletal networks, and the interaction of actin with membranes. Examples of these various modes of Ca2+-dependent regulation of cytoskeletal structure and contractility are discussed.Entities:
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Year: 1986 PMID: 3792141 DOI: 10.1002/9780470513347.ch14
Source DB: PubMed Journal: Ciba Found Symp ISSN: 0300-5208