The cytogenetics of solid tumors. Relation to diagnosis, classification and pathology.

This overview discusses the chromosome changes in solid tumors and how recent advancements in techniques have yielded results which at least qualitatively are similar to those obtained in the leukemias, i.e., that consistent and recurrent chromosome changes characterize most tumors adequately examined and that tumor entities consist of cytogenetically defined and unique subsets. Thus, the findings point to a similar application of the chromosome changes in tumors in their classification, diagnosis and causation.