Literature DB >> 3788039

Two fatalities resulting from Tessalon (benzonatate).

J A Cohan, T J Manning, L Lukash, C Long, K R Ziminski, S E Conradi.   

Abstract

Two fatal cases involving Tessalon (benzonatate) were quantitated by ultraviolet (UV) and high performance liquid chromatography (HPLC). The first case involved an infant found choking; Tessalon perles were found with the child. The second case involved a successful suicide of an 18-year-old that consumed a "handful" of phenytoin and benzonatate and expired within 1 hr of the ingestion. Blood, brain and kidney concentrations are reported. These are believed to be the first two reported cases involving this compound.

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Year:  1986        PMID： 3788039

Source DB:  PubMed          Journal:  Vet Hum Toxicol        ISSN： 0145-6296


  5 in total

1.  Benzonatate Ingestion Reported to the National Poison Center Database System (NPDS).

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Journal:  J Med Toxicol       Date:  2010-12

2.  Benzonatate Overdose Presenting as Cardiac Arrest with Rapidly Narrowing QRS Interval.

Authors:  Robert J Stephens; Ari B Filip; Kevin T Baumgartner; Evan S Schwarz; David B Liss
Journal:  J Med Toxicol       Date:  2022-07-05

3.  Benzonatate toxicity in a teenager resulting in coma, seizures, and severe metabolic acidosis.

Authors:  Daniel A Thimann; Craig J Huang; Collin S Goto; Sing-Yi Feng
Journal:  J Pediatr Pharmacol Ther       Date:  2012-07

Review 4.  Chronic Cough in Adults: Make the Diagnosis and Make a Difference.

Authors:  Alan G Kaplan
Journal:  Pulm Ther       Date:  2019-03-13

Review 5.  Antitussives and substance abuse.

Authors:  Jarrett M Burns; Edward W Boyer
Journal:  Subst Abuse Rehabil       Date:  2013-11-06
  5 in total

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