Literature DB >> 3787904

Tobramycin and renal ischemia.

J A Wilson, R L Hackett, B Finlayson.   

Abstract

Sprague-Dawley rats were injected with known nephrotoxic doses of tobramycin and then subjected to varying amounts of warm renal ischemia. Analysis of serum creatinine at the time of sacrifice revealed no statistically significant difference among controls and the two doses of tobramycin at any given duration of ischemia. Light microscopy revealed no worsening of tubular necrosis with increasing doses of tobramycin.

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Year:  1986        PMID: 3787904     DOI: 10.1016/0090-4295(86)90075-0

Source DB:  PubMed          Journal:  Urology        ISSN: 0090-4295            Impact factor:   2.649


  1 in total

1.  Altered tobramycin pharmacokinetics during chemoprophylaxis in bladder surgery.

Authors:  F Bressolle; P Joubert; A Gouby; P Costa; M Laracine; T Rebière
Journal:  Antimicrob Agents Chemother       Date:  1991-07       Impact factor: 5.191

  1 in total

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