| Literature DB >> 3786603 |
J I Nurnberger, W H Berrettini, S Simmons-Alling, J J Guroff, E S Gershon.
Abstract
Seven persons (three normal volunteers and four euthymic bipolar patients) received one to four doses of gamma-aminobutyric acid (GABA) intravenously. All subjects reported dysphoria, and their mood disturbance scores on the Profile of Mood States were significantly increased in a dose-related fashion. Placebo infusions did not produce similar responses. Mood disturbance was accompanied by a dose-related increase in pulse and blood pressure.Entities:
Mesh：
Substances：
Year: 1986 PMID： 3786603 DOI： 10.1016/0165-1781(86)90004-1
Source DB: PubMed Journal: Psychiatry Res ISSN： 0165-1781 Impact factor: 3.222