Literature DB >> 3785577

Anticonvulsant effects of ivermectin in genetically-epileptic chickens.

E C Crichlow, P R Mishra, R D Crawford.   

Abstract

In genetically-photosensitive epileptic chickens, the anti-parasitic agent ivermectin, at 1.0 and 5.0 mg/kg, decreased or prevented seizures induced by intermittent photic stimulation without any side-effects on the central nervous system. The latency and duration of this anti-convulsant effect was dose-dependent. When combined with diazepam, ivermectin prolonged the anti-convulsant action of diazepam.

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Year:  1986        PMID: 3785577     DOI: 10.1016/0028-3908(86)90154-1

Source DB:  PubMed          Journal:  Neuropharmacology        ISSN: 0028-3908            Impact factor:   5.250


  3 in total

1.  The effect of protein binding on ivermectin uptake by bovine brain microvessel endothelial cells.

Authors:  K L Audus; S R Knaub; F L Guillot; J M Schaeffer
Journal:  Vet Res Commun       Date:  1992       Impact factor: 2.459

2.  In vivo protection against strychnine toxicity in mice by the glycine receptor agonist ivermectin.

Authors:  Ahmed Maher; Rasha Radwan; Hans-Georg Breitinger
Journal:  Biomed Res Int       Date:  2014-09-15       Impact factor: 3.411

3.  Causal Interrogation of Neuronal Networks and Behavior through Virally Transduced Ivermectin Receptors.

Authors:  Horst A Obenhaus; Andrei Rozov; Ilaria Bertocchi; Wannan Tang; Joachim Kirsch; Heinrich Betz; Rolf Sprengel
Journal:  Front Mol Neurosci       Date:  2016-08-30       Impact factor: 5.639

  3 in total

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