Literature DB >> 3785550

Polysomes during early postnatal development of brain in the rat.

D Gauthier, M R Ven Murthy.   

Abstract

We have attempted to show eventual modifications in the brain protein synthesis apparatus of rat during the first three weeks after birth. Through this time we noted a steady decrease (about 60%) in the free polysomes, when expressed relative to tissue weight. This decrease does not correlate with changes in the polysome profile, indicating that no loss in the efficiency of protein synthesis was involved. Translation in a reticulocyte lysate also failed to reveal differences.

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Year:  1986        PMID: 3785550     DOI: 10.1007/bf00966130

Source DB:  PubMed          Journal:  Neurochem Res        ISSN: 0364-3190            Impact factor:   3.996


  17 in total

1.  Changes in polysomes of the developing rat brain.

Authors:  S Yamagami; K Mori
Journal:  J Neurochem       Date:  1970-06       Impact factor: 5.372

2.  Magnesium precipitation of ribonucleoprotein complexes. Expedient techniques for the isolation of undergraded polysomes and messenger ribonucleic acid.

Authors:  R D Palmiter
Journal:  Biochemistry       Date:  1974-08-13       Impact factor: 3.162

3.  Free and membrane-bound ribosomes of rat cerebral cortex. Protein synthesis in vivo and in vitro.

Authors:  M R Murthy
Journal:  J Biol Chem       Date:  1972-03-25       Impact factor: 5.157

4.  Regulation of protein synthesis in developing mouse brain tissue. Alteration in ribosomal activity.

Authors:  M P Lerner; T C Johnson
Journal:  J Biol Chem       Date:  1970-03-25       Impact factor: 5.157

5.  Developmental effects on protein synthesis rates in regions of the CNS in vivo and in vitro.

Authors:  D S Dunlop; W van Elden; A Lajtha
Journal:  J Neurochem       Date:  1977-12       Impact factor: 5.372

6.  In vitro biosynthesis of tubulin on total, free and membrane-bound polysomes from the developing rat brain.

Authors:  M Sato; Y Yoshida; Y Takahashi
Journal:  J Neurochem       Date:  1978-12       Impact factor: 5.372

Review 7.  Regulation of protein synthesis during postnatal maturation of the brain.

Authors:  T C Johnson
Journal:  J Neurochem       Date:  1976-07       Impact factor: 5.372

Review 8.  Turnover of protein in the nervous system.

Authors:  A Lajtha; D Dunlop
Journal:  Life Sci       Date:  1981-08-24       Impact factor: 5.037

9.  Rodent brain growth stages: an analytical review.

Authors:  A Gottlieb; I Keydar; H T Epstein
Journal:  Biol Neonate       Date:  1977

10.  Age-dependent changes in brain protein synthesis in the rat.

Authors:  J L Fando; M Salinas; C G Wasterlain
Journal:  Neurochem Res       Date:  1980-04       Impact factor: 3.996

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