Literature DB >> 378536

The Ah locus: genetic regulation of the metabolism of carcinogens, drugs, and other environmental chemicals by cytochrome P-450-mediated monooxygenases.

D W Nebert, N M Jensen.   

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Year:  1979        PMID: 378536     DOI: 10.3109/10409237909105427

Source DB:  PubMed          Journal:  CRC Crit Rev Biochem        ISSN: 0045-6411


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  42 in total

Review 1.  Multiple forms of inducible drug-metabolizing enzymes: a reasonable mechanism by which any organism can cope with adversity.

Authors:  D W Nebert
Journal:  Mol Cell Biochem       Date:  1979-09-28       Impact factor: 3.396

2.  Human cytochrome P-450 PB-1: a multigene family involved in mephenytoin and steroid oxidations that maps to chromosome 10.

Authors:  R R Meehan; J R Gosden; D Rout; N D Hastie; T Friedberg; M Adesnik; R Buckland; V van Heyningen; J Fletcher; N K Spurr
Journal:  Am J Hum Genet       Date:  1988-01       Impact factor: 11.025

3.  O-dealkylation of resorufin ethers as an indicator of hepatic cytochrome P-450 isoenzyme induction in the cotton rat (Sigmodon hispidus): a method for monitoring environmental contamination.

Authors:  C S Elangbam; C W Qualls; R L Lochmiller
Journal:  Bull Environ Contam Toxicol       Date:  1991-07       Impact factor: 2.151

4.  Regulation of phenobarbital-inducible cytochrome P-450s in rat and mouse liver following dexamethasone administration and hypophysectomy.

Authors:  R R Meehan; L M Forrester; K Stevenson; N D Hastie; A Buchmann; H W Kunz; C R Wolf
Journal:  Biochem J       Date:  1988-09-15       Impact factor: 3.857

5.  Cell-specific induction of mouse Cyp1a1 mRNA during development.

Authors:  A Dey; H Westphal; D W Nebert
Journal:  Proc Natl Acad Sci U S A       Date:  1989-10       Impact factor: 11.205

Review 6.  Long-term carcinogenesis studies on 2,3,7,8-tetrachlorodibenzo-p-dioxin and hexachlorodibenzo-p-dioxins.

Authors:  J E Huff; A G Salmon; N K Hooper; L Zeise
Journal:  Cell Biol Toxicol       Date:  1991-01       Impact factor: 6.691

7.  Nitrofurantoin cytotoxicity. In vitro assessment of risk based on glutathione metabolism.

Authors:  S P Spielberg; G B Gordon
Journal:  J Clin Invest       Date:  1981-01       Impact factor: 14.808

8.  Tissue-specific expression of the mouse dioxin-inducible P(1)450 and P(3)450 genes: differential transcriptional activation and mRNA stability in liver and extrahepatic tissues.

Authors:  S Kimura; F J Gonzalez; D W Nebert
Journal:  Mol Cell Biol       Date:  1986-05       Impact factor: 4.272

9.  Toxicity and EROD-inducing potency of 24 polycyclic aromatic hydrocarbons (PAHs) in chick embryos.

Authors:  B Brunström; D Broman; C Näf
Journal:  Arch Toxicol       Date:  1991       Impact factor: 5.153

Review 10.  The role of conjugation reactions in detoxication.

Authors:  K W Bock; W Lilienblum; G Fischer; G Schirmer; B S Bock-Henning
Journal:  Arch Toxicol       Date:  1987       Impact factor: 5.153

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