Evaluation of albumin-globulin ratio to confirm the clinical stages of sarcoidosis.

The serum albumin-globulin ratio (A/G) has been evaluated and correlated to confirm the clinical stages of sarcoidosis in clinically diagnosed cases. In comparing each clinical stage of sarcoidosis, using Student's t test (P = .05), a significant difference was observed. Overall, men maintained a higher A/G ratio than women in all of the clinical stages. The authors conclude that the serum A/G ratio, which can be computed from serum analyses of albumin and globulins by a suitable method, can be an additional and reliable index requiring no extra serum sample or cost per test to confirm clinical stages of sarcoidosis. This measurement can easily be used in monitoring the progression of disease or efficacy of the therapy.