Literature DB >> 3781708

Release of cytolytic factor(s) by murine macrophages in vitro on treatment with cis-platin.

A Sodhi, S M Singh.   

Abstract

Supernatants collected from macrophage monolayers treated with cis-Platin lyse the tumor cells in vitro. In addition the cis-Platin treated macrophages are observed to show increased binding of tumor cells and also have a cytostatic effect on them. It is proposed that cis-Platin treatment of macrophages results in the release of cytolytic factor(s) with potent capacity to lyse the tumor cells in vitro.

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Year:  1986        PMID： 3781708     DOI： 10.1016/0192-0561(86)90005-6

Source DB:  PubMed          Journal:  Int J Immunopharmacol        ISSN： 0192-0561


  4 in total

1.  Production of TNF-alpha, IL-1beta, IL-12 and IFN-gamma in murine peritoneal macrophages on treatment with wheat germ agglutinin in vitro: involvement of tyrosine kinase pathways.

Authors:  Ajit Sodhi; Varun Kesherwani
Journal:  Glycoconj J       Date:  2007-08-01       Impact factor: 2.916

2.  Effect of interferon-gamma priming on the activation of murine peritoneal macrophages to tumouricidal state by cisplatin, IL-1, and tumour necrosis factor (TNF): production of IL-1 and TNF.

Authors:  A Sodhi; R K Singh; S M Singh
Journal:  Clin Exp Immunol       Date:  1992-05       Impact factor: 4.330

3.  Role of mitogen-activated protein kinases in peptidoglycan-induced expression of inducible nitric oxide synthase and nitric oxide in mouse peritoneal macrophages: extracellular signal-related kinase, a negative regulator.

Authors:  Kunal H Bhatt; Ajit Sodhi; Rituparna Chakraborty
Journal:  Clin Vaccine Immunol       Date:  2011-03-30

4.  Mycobacterium indicus pranii supernatant induces apoptotic cell death in mouse peritoneal macrophages in vitro.

Authors:  Rajeev Kumar Pandey; Kunal H Bhatt; Yogesh Dahiya; Ajit Sodhi
Journal:  PLoS One       Date:  2011-02-11       Impact factor: 3.240
  4 in total

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