Literature DB >> 3781409

An evaluation of three in vitro cytotoxicity assays.

R J Riddell, R H Clothier, M Balls.   

Abstract

A number of methods for determining the general toxic effects of test chemicals on cells in culture are now at the validation stage. Three such methods based on measurement of total cell protein or neutral red uptake and on the detection of morphological effects have been compared. The cell line used was 3T3-L1 (a continuous fibroblast cell line derived from mouse embryos). The results obtained in a blind trial with 30 coded chemicals indicated a close correlation between the relative cytotoxicities of chemicals tested by all three methods.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 3781409     DOI： 10.1016/0278-6915(86)90095-5

Source DB:  PubMed          Journal:  Food Chem Toxicol        ISSN： 0278-6915            Impact factor:   6.023


  10 in total

1.  One-pot synthesis of pH-responsive hybrid nanogel particles for the intracellular delivery of small interfering RNA.

Authors:  Sm Z Khaled; Armando Cevenini; Iman K Yazdi; Alessandro Parodi; Michael Evangelopoulos; Claudia Corbo; Shilpa Scaria; Ye Hu; Seth G Haddix; Bruna Corradetti; Francesco Salvatore; Ennio Tasciotti
Journal:  Biomaterials       Date:  2016-01-27       Impact factor: 12.479

2.  The enhancement of phase 2 enzyme activities by sodium butyrate in normal intestinal epithelial cells is associated with Nrf2 and p53.

Authors:  Keisuke Yaku; Yuka Enami; Chika Kurajyo; Isao Matsui-Yuasa; Yotaro Konishi; Akiko Kojima-Yuasa
Journal:  Mol Cell Biochem       Date:  2012-07-18       Impact factor: 3.396

3.  Monoclonal antibody to Shiga toxin 2 which blocks receptor binding and neutralizes cytotoxicity.

Authors:  H Nakao; N Kiyokawa; J Fujimoto; S Yamasaki; T Takeda
Journal:  Infect Immun       Date:  1999-11       Impact factor: 3.441

4.  Assessment of chemical toxicity using mammalian mitochondrial electron transport particles.

Authors:  L M Knobeloch; G A Blondin; H W Read; J M Harkin
Journal:  Arch Environ Contam Toxicol       Date:  1990 Nov-Dec       Impact factor: 2.804

5.  Violacein cytotoxicity and induction of apoptosis in V79 cells.

Authors:  P S Melo; S S Maria; B C Vidal; M Haun; N Durán
Journal:  In Vitro Cell Dev Biol Anim       Date:  2000-09       Impact factor: 2.416

6.  Shiga toxin-associated hemolytic uremic syndrome: combined cytotoxic effects of shiga toxin and lipopolysaccharide (endotoxin) on human vascular endothelial cells in vitro.

Authors:  C B Louise; T G Obrig
Journal:  Infect Immun       Date:  1992-04       Impact factor: 3.441

7.  Shiga toxin-associated hemolytic-uremic syndrome: combined cytotoxic effects of Shiga toxin, interleukin-1 beta, and tumor necrosis factor alpha on human vascular endothelial cells in vitro.

Authors:  C B Louise; T G Obrig
Journal:  Infect Immun       Date:  1991-11       Impact factor: 3.441

8.  Shiga toxin-associated hemolytic uremic syndrome: interleukin-1 beta enhancement of Shiga toxin cytotoxicity toward human vascular endothelial cells in vitro.

Authors:  S A Kaye; C B Louise; B Boyd; C A Lingwood; T G Obrig
Journal:  Infect Immun       Date:  1993-09       Impact factor: 3.441

9.  Colostrum from healthy Brazilian women inhibits adhesion and contains IgA antibodies reactive with Shiga toxin-producing Escherichia coli.

Authors:  Patricia Palmeira; Solange Barros Carbonare; José Araujo Amaral; Milene Tino-De-Franco; Magda Maria Sales Carneiro-Sampaio
Journal:  Eur J Pediatr       Date:  2004-11-10       Impact factor: 3.183

10.  Exploring wild Aspleniaceae ferns as safety sources of polyphenols: The case of Asplenium trichomanes L. and Ceterach officinarum Willd.

Authors:  Adrià Farràs; Montserrat Mitjans; Filippo Maggi; Giovanni Caprioli; María Pilar Vinardell; Víctor López
Journal:  Front Nutr       Date:  2022-09-12
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.