| Literature DB >> 3781408 |
P Knox, P F Uphill, J R Fry, J Benford, M Balls.
Abstract
An in vitro method for assessing the relative acute toxicities of chemicals was developed through the collaboration of four tissue culture laboratories. Cytotoxicity was measured by using a dye-binding method to determine inhibition of the proliferation of BCL-D1 cells 72 hr after addition of the test chemical. A blind trial with 50 chemicals showed that the test procedure gave results with a high degree of interlaboratory reproducibility.Entities:
Mesh:
Year: 1986 PMID: 3781408 DOI: 10.1016/0278-6915(86)90092-x
Source DB: PubMed Journal: Food Chem Toxicol ISSN: 0278-6915 Impact factor: 6.023