Literature DB >> 3781408

The FRAME multicentre project on in vitro cytotoxicology.

P Knox, P F Uphill, J R Fry, J Benford, M Balls.   

Abstract

An in vitro method for assessing the relative acute toxicities of chemicals was developed through the collaboration of four tissue culture laboratories. Cytotoxicity was measured by using a dye-binding method to determine inhibition of the proliferation of BCL-D1 cells 72 hr after addition of the test chemical. A blind trial with 50 chemicals showed that the test procedure gave results with a high degree of interlaboratory reproducibility.

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Year:  1986        PMID: 3781408     DOI: 10.1016/0278-6915(86)90092-x

Source DB:  PubMed          Journal:  Food Chem Toxicol        ISSN: 0278-6915            Impact factor:   6.023


  15 in total

1.  The methylene blue colorimetric microassay for determining cell line response to growth factors.

Authors:  M F Dent; L Hubbold; H Radford; A P Wilson
Journal:  Cytotechnology       Date:  1995-02       Impact factor: 2.058

2.  Assessing organic toxic pollutants in fish-canning factory effluents using cultured fish cells.

Authors:  M M Vega; A Castaño; T Blazquez; J V Tarazona
Journal:  Ecotoxicology       Date:  1994-06       Impact factor: 2.823

Review 3.  In vitro models.

Authors:  D Anderson
Journal:  Drug Saf       Date:  1990       Impact factor: 5.606

4.  Acute toxicity of selected metals and phenols on RTG-2 and CHSE-214 fish cell lines.

Authors:  A Castaño; M M Vega; J V Tarazona
Journal:  Bull Environ Contam Toxicol       Date:  1995-08       Impact factor: 2.151

5.  ATP assay on cell monolayers as an index of cytotoxicity.

Authors:  A Castaño; J V Tarazona
Journal:  Bull Environ Contam Toxicol       Date:  1994-08       Impact factor: 2.151

6.  Ecotoxicity evaluation and human risk assessment of an agricultural polluted soil.

Authors:  Imad El-Alam; Anthony Verdin; Joël Fontaine; Frédéric Laruelle; Ramez Chahine; Hassane Makhlouf; Anissa Lounès-Hadj Sahraoui
Journal:  Environ Monit Assess       Date:  2018-11-20       Impact factor: 2.513

7.  Assessment of chemical toxicity using mammalian mitochondrial electron transport particles.

Authors:  L M Knobeloch; G A Blondin; H W Read; J M Harkin
Journal:  Arch Environ Contam Toxicol       Date:  1990 Nov-Dec       Impact factor: 2.804

8.  Metallothionein induction in cultured fibroblasts and liver of a marine flatfish, the turbot,Scophthalmus maximus.

Authors:  S George; D Burgess; M Leaver; N Frerichs
Journal:  Fish Physiol Biochem       Date:  1992-05       Impact factor: 2.794

9.  Intracellular lactate dehydrogenase concentration as an index of cytotoxicity in rat hepatocyte primary culture.

Authors:  E S Chao; D Dunbar; L S Kaminsky
Journal:  Cell Biol Toxicol       Date:  1988-03       Impact factor: 6.691

10.  MEIC--a new international multicenter project to evaluate the relevance to human toxicity of in vitro cytotoxicity tests.

Authors:  I Bondesson; B Ekwall; S Hellberg; L Romert; K Stenberg; E Walum
Journal:  Cell Biol Toxicol       Date:  1989-11       Impact factor: 6.691

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