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Literature DB >> 3780823

Quantitation of the renal effect of calcitonin in the hypercalcaemia of malignancy.

Abstract

The renal effect of calcitonin (independent of changes due to variations in sodium excretion) was quantitated in malignancy associated hypercalcaemia. There was considerable inter- and intra-patient variability in response but this was unaffected by tumour type. Humoral hypercalcaemia tended to be resistant to control. In responsive patients the renal effects of calcitonin unlike those described in bone did not diminish with time.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Calcitonin
Sodium
Calcium

Year: 1986 PMID： 3780823 DOI： 10.1007/bf00870981

Source DB: PubMed Journal: Eur J Clin Pharmacol ISSN： 0031-6970 Impact factor: 2.953

28 in total

Review 1. Calcitonin binding sites in bone: relationships to biological response and "escape".

Authors: A H Tashjian; D R Wright; J L Ivey; A Pont
Journal: Recent Prog Horm Res Date: 1978

2. New approach to the treatment of hypercalcemia. The effect of short-term treatment with mithramycin.

Authors: R E Slayton; B I Shnider; E Elias; J Horton; C P Perlia
Journal: Clin Pharmacol Ther Date: 1971 Sep-Oct Impact factor: 6.875

Review 3. Thyrocalcitonin.

Authors: P F Hirsch; P L Munson
Journal: Physiol Rev Date: 1969-07 Impact factor: 37.312

Quantitation of the renal effect of calcitonin in the hypercalcaemia of malignancy.

Review 1. Calcitonin binding sites in bone: relationships to biological response and "escape".

2. New approach to the treatment of hypercalcemia. The effect of short-term treatment with mithramycin.

Review 3. Thyrocalcitonin.

4. Adenylate cyclase responsiveness to hormones in various portions of the human nephron.

5. Rehydration in the treatment of severe hypercalcaemia.

6. Acute treatment with calcitonin in primary hyperparathyroidism and severe hypercalcaemia of other origin.

7. Effect of calcitonin and glutocorticoids in combination on the hypercalcemia of malignancy.

8. Postabsorptive urinary hydroxyproline test in patients with metastatic bone disease from breast cancer.

9. Inhibition of osteolytic bone lesions by (3-amino-1-hydroxypropylidene)-1, 1-bisphosphonate (A.P.D.).

Review 10. Cancer and the kidney: complications of neoplasms.

Review 1. Assessment of renal and skeletal components of hypercalcemia.

2. Potentiation of calcitonin by corticosteroids during the treatment of the hypercalcaemia of malignancy.

Review 3. Current management of malignant hypercalcaemia.

Review 4. Drugs used in the treatment of metabolic bone disease. Clinical pharmacology and therapeutic use.