Literature DB >> 3779002

Salt-induced aggregation and fusion of dioctadecyldimethylammonium chloride and sodium dihexadecylphosphate vesicles.

A M Carmona-Ribeiro, H Chaimovich.   

Abstract

Small dioctadecyldimethylammonium chloride (DODAC) vesicles prepared by sonication fuse upon addition of NaCl as detected by several methods (electron microscopy, trapped volume determinations, temperature-dependent phase transition curves, and osmometer behavior. In contrast, small sodium dihexadecyl phosphate (DHP) vesicles mainly aggregate upon NaCl addition as shown by electron microscopy and the lack of osmometer behavior. Scatter-derived absorbance changes of small and large DODAC or DHP vesicles as a function of time after salt addition were obtained for a range of NaCl or amphiphile concentration. These changes were interpreted in accordance with a phenomenological model based upon fundamental light-scattering laws and simple geometrical considerations. Short-range hydration repulsion between DODAC (or DHP) vesicles is possibly the main energy barrier for the fusion process.

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Year:  1986        PMID: 3779002      PMCID: PMC1329839          DOI: 10.1016/S0006-3495(86)83501-9

Source DB:  PubMed          Journal:  Biophys J        ISSN: 0006-3495            Impact factor:   4.033


  16 in total

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5.  Ca2+-induced fusion of phospholipid vesicles monitored by mixing of aqueous contents.

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Authors:  C F Schmidt; D Lichtenberg; T E Thompson
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9.  Formation of closed vesicles from a simple phosphate diester. Preparation and some properties of vesicles of dihexadecyl phosphate.

Authors:  R A Mortara; F H Quina; H Chaimovich
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10.  Effects of temperature and lipid composition on the serum albumin-induced aggregation and fusion of small unilamellar vesicles.

Authors:  S Schenkman; P S Araujo; R Dijkman; F H Quina; H Chaimovich
Journal:  Biochim Biophys Acta       Date:  1981-12-21
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  10 in total

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