Literature DB >> 3778930

Importance of human gastric lipase for intestinal lipolysis: an in vitro study.

Y Gargouri, G Pieroni, C Rivière, P A Lowe, J F Saunière, L Sarda, R Verger.   

Abstract

Using soybean triacylglycerols emulsified with egg lecithin we have studied, in vitro, the influence of substrate prehydrolysis by human gastric lipase upon subsequent degradation by the pancreatic lipase-co-lipase system. Fatty acids liberated by pure human gastric lipase or juice trigger immediate activity of human pancreatic lipase. Gastric lipolysis appears to be of prime importance for dietary lipid digestion in human.

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Year:  1986        PMID： 3778930     DOI： 10.1016/0005-2760(86)90234-1

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  17 in total

Review 1.  Human pancreatic digestive enzymes.

Authors:  David C Whitcomb; Mark E Lowe
Journal:  Dig Dis Sci       Date:  2007-01-05       Impact factor: 3.199

2.  INFOGEST static in vitro simulation of gastrointestinal food digestion.

Authors:  André Brodkorb; Lotti Egger; Marie Alminger; Paula Alvito; Ricardo Assunção; Simon Ballance; Torsten Bohn; Claire Bourlieu-Lacanal; Rachel Boutrou; Frédéric Carrière; Alfonso Clemente; Milena Corredig; Didier Dupont; Claire Dufour; Cathrina Edwards; Matt Golding; Sibel Karakaya; Bente Kirkhus; Steven Le Feunteun; Uri Lesmes; Adam Macierzanka; Alan R Mackie; Carla Martins; Sébastien Marze; David Julian McClements; Olivia Ménard; Mans Minekus; Reto Portmann; Cláudia N Santos; Isabelle Souchon; R Paul Singh; Gerd E Vegarud; Martin S J Wickham; Werner Weitschies; Isidra Recio
Journal:  Nat Protoc       Date:  2019-03-18       Impact factor: 13.491

Review 3.  Novel functions of PXR in cardiometabolic disease.

Authors:  Changcheng Zhou
Journal:  Biochim Biophys Acta       Date:  2016-02-26

4.  The complete digestion of human milk triacylglycerol in vitro requires gastric lipase, pancreatic colipase-dependent lipase, and bile salt-stimulated lipase.

Authors:  S Bernbäck; L Bläckberg; O Hernell
Journal:  J Clin Invest       Date:  1990-04       Impact factor: 14.808

Review 5.  Lipids in the Stomach - Implications for the Evaluation of Food Effects on Oral Drug Absorption.

Authors:  Mirko Koziolek; Frédéric Carrière; Christopher J H Porter
Journal:  Pharm Res       Date:  2018-02-08       Impact factor: 4.200

6.  Lipid lateral organization in fluid interfaces controls the rate of colipase association.

Authors:  I P Sugar; N K Mizuno; M M Momsen; H L Brockman
Journal:  Biophys J       Date:  2001-12       Impact factor: 4.033

7.  Release of nonesterified fatty acids during cerulein-induced pancreatitis in rats.

Authors:  F Paye; J Chariot; G Molas; J Benessiano; C Rozé
Journal:  Dig Dis Sci       Date:  1996-10       Impact factor: 3.199

Review 8.  Pancreatic enzymes in chronic pancreatitis.

Authors:  P Layer; G Holtmann
Journal:  Int J Pancreatol       Date:  1994-02

9.  In vitro gastrointestinal lipolysis of four formulations of piroxicam and cinnarizine with the self emulsifying excipients Labrasol and Gelucire 44/14.

Authors:  Sylvie Fernandez; Stéphanie Chevrier; Nicolas Ritter; Bruno Mahler; Frédéric Demarne; Frédéric Carrière; Vincent Jannin
Journal:  Pharm Res       Date:  2009-05-19       Impact factor: 4.200

10.  In vitro effects of fat, FA, and cholesterol on sphingomyelin hydrolysis induced by rat intestinal alkaline sphingomyelinase.

Authors:  Jian-Jun Liu; Ake Nilsson; Rui-Dong Duan
Journal:  Lipids       Date:  2002-05       Impact factor: 1.880
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