Literature DB >> 3776356

[Etryptamine, a new designer drug with a fatal effect].

T Daldrup, C Heller, U Matthiesen, S Honus, A Bresges, K Haarhoff.   

Abstract

Capsules with etryptamine have been commonly available on the market since the middle of 1985. Up to 1962 this CNS-stimulating, monoamine-oxidase-inhibiting drug was sold as an antidepressant (Monase). A case of fatal intoxication is reported. The exact amount of etryptamine taken several hours before death are not known, but it could have been in the range of 700 mg. This drug was detected in tissue by means of common analytical techniques (GLC, GC-MS, HPLC, TLC). Etryptamine cross-reacts with the Emit-st amphetamine assay and can also be detected in urine using these techniques. The level in postmortem blood was 1.1 mg/l. The effects the young man showed were like those known from intoxication with amphetamines, MAO inhibitors, and thymoleptics. Malignant hyperthermia is discussed as a possible cause of death. It is suggested that trade in etryptamine should be controlled.

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Year:  1986        PMID: 3776356     DOI: 10.1007/bf00200960

Source DB:  PubMed          Journal:  Z Rechtsmed        ISSN: 0044-3433


  18 in total

1.  Metabolic studies with 3-(2-aminobutyl-1-C14) indole acetate [monase-C14]. I. Distribution and excretion in rat, dog, and man.

Authors:  F S EBERTS
Journal:  J Neuropsychiatr       Date:  1961-02

2.  The pharmacology of etryptamine.

Authors:  M E GREIG; P H SEAY; W A FREYBURGER
Journal:  J Neuropsychiatr       Date:  1961-02

3.  Toxicologic effects of etryptamine in experimental animals.

Authors:  J E GRAY
Journal:  J Neuropsychiatr       Date:  1961-02

4.  A new and safer monoamine oxidase inhibitor.

Authors:  T R ROBIE
Journal:  J Neuropsychiatr       Date:  1961-02

5.  Etryptamine in neuropediatrics.

Authors:  M A PERLSTEIN
Journal:  J Neuropsychiatr       Date:  1961-02

6.  Clinical studies with ethyltryptamine.

Authors:  W J TURNER; S MERLIS
Journal:  J Neuropsychiatr       Date:  1961-02

7.  Treatment of geriatric patients with etryptamine acetate.

Authors:  A J KIESSLING
Journal:  J Neuropsychiatr       Date:  1961-02

8.  Effects in normal man of alpha-methyltryptamine and alpha-ethyltryptamine.

Authors:  H B MURPHREE; R H DIPPY; E H JENNEY; C C PFEIFFER
Journal:  Clin Pharmacol Ther       Date:  1961 Nov-Dec       Impact factor: 6.875

9.  [On histomorphological changes of the heart and skeleton muscles in malignant hyperpyrexia (author's transl)].

Authors:  B Brinkmann; K Püschel
Journal:  Z Rechtsmed       Date:  1977-08-26

10.  Fatal malignant hyperthermia as a result of ingestion of tranylcypromine (Parnate) combined with white wine and cheese.

Authors:  H Mirchandani; L E Reich
Journal:  J Forensic Sci       Date:  1985-01       Impact factor: 1.832

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  4 in total

1.  alpha-Ethyltryptamine (alpha-ET) as a discriminative stimulus in rats.

Authors:  Richard A Glennon; Tatiana Bondareva; Richard Young
Journal:  Pharmacol Biochem Behav       Date:  2006-11-16       Impact factor: 3.533

2.  Behavioral characterization of alpha-ethyltryptamine, a tryptamine derivative with MDMA-like properties in rats.

Authors:  K M Krebs; M A Geyer
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

Review 3.  Recreational use, analysis and toxicity of tryptamines.

Authors:  Roberta Tittarelli; Giulio Mannocchi; Flaminia Pantano; Francesco Saverio Romolo
Journal:  Curr Neuropharmacol       Date:  2015-01       Impact factor: 7.363

Review 4.  Toxicology and Analysis of Psychoactive Tryptamines.

Authors:  Sara Malaca; Alfredo Fabrizio Lo Faro; Alice Tamborra; Simona Pichini; Francesco Paolo Busardò; Marilyn A Huestis
Journal:  Int J Mol Sci       Date:  2020-12-04       Impact factor: 5.923

  4 in total

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