Literature DB >> 377495

Toxaphene, a complex mixture of polychloroterpenes and a major insecticide, is mutagenic.

N K Hooper, B N Ames, M A Saleh, J E Casida.   

Abstract

Toxaphene, the most widely used chlorinated insecticide, is mutagenic in the Salmonella test without requiring liver homogenate for activity. This insecticide is a complex mixture (more than 177 polychloroterpenes) with carcinogenic activity in rodents. Some but not all of the mutagenic components are easily separated from the insecticidal ingredients.

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Year:  1979        PMID： 377495     DOI： 10.1126/science.377495

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  5 in total

1.  Metabolism of toxaphene by the isolated perfused bovine liver.

Authors:  R M Maiorino; F M Whiting; W H Brown; B L Reid; J W Stull
Journal:  Arch Environ Contam Toxicol       Date:  1984-09       Impact factor: 2.804

2.  Effect of toxaphene, camphene, and cedar oil on methyl parathion residues on cotton.

Authors:  W S Bigley; F W Plapp; R L Hanna; J A Harding
Journal:  Bull Environ Contam Toxicol       Date:  1981-07       Impact factor: 2.151

3.  Biological stability of toxaphene in estuarine sediment.

Authors:  F H Weber; F A Rosenberg
Journal:  Bull Environ Contam Toxicol       Date:  1980-07       Impact factor: 2.151

4.  Cytokinetic and cytogenetic effect of agricultural chemicals on human lymphoid cells in vitro. II. Organochlorine pesticides.

Authors:  R C Sobti; A Krishan; J Davies
Journal:  Arch Toxicol       Date:  1983-03       Impact factor: 5.153

Review 5.  Environmental occurrence, analysis, and toxicology of toxaphene compounds.

Authors:  H J de Geus; H Besselink; A Brouwer; J Klungsøyr; B McHugh; E Nixon; G G Rimkus; P G Wester; J de Boer
Journal:  Environ Health Perspect       Date:  1999-02       Impact factor: 9.031
  5 in total

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