| Literature DB >> 3774129 |
C Reavill, I P Stolerman, R Kumar, H S Garcha.
Abstract
Intraventricular microinjection (5 micrograms) of the bisquaternary ganglion-blocking drug chlorisondamine prevented acquisition of nicotine-induced conditioned taste aversion (CTA) in rats. This appeared to be a specific effect because chlorisondamine did not attenuate the conditioned taste aversion caused by apomorphine. These results support findings from other behavioural procedures indicating that centrally administered chlorisondamine causes a long-term blockade of central nicotinic mechanisms.Entities:
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Year: 1986 PMID: 3774129 DOI: 10.1016/0028-3908(86)90204-2
Source DB: PubMed Journal: Neuropharmacology ISSN: 0028-3908 Impact factor: 5.250